Enzyme Inhibitor from Marine Organisms

• Weitere Verfasser: Tischler, Dirk (Herausgegeben von)
• Format: Elektronisch Buchkapitel
• Sprache: Englisch
• Veröffentlicht: Basel, Switzerland MDPI - Multidisciplinary Digital Publishing Institute 2020
• Schlagworte: Research & information: general; sponge Monanchora pulchra; pentacyclic guanidine alkaloids; GH36 α-galactosidase; GH109 α-N-acetylgalactosaminidase; slow-binding irreversible inhibitor; monanchomycalin B; monanhocidin A; normonanhocidin A; Alzheimer's disease; BACE1; acetylcholinesterase; in silico docking; phlorotannins; Ulva intestinalis; ACE inhibitory peptide; optimization; purification; structural identification; molecular docking; secondary metabolites; Mycosphaerella sp.; asperchalasine; α-glucosidase; kinase inhibitors; drug development; marine natural products; inhibitor; macroalgae; marine fish; protease; Ulva ohnoi; functional annotation; structure-function relation; natural products; bioactives; enzyme inhibition; inactivation; marine bacteria; marine fungi; marine sponges
• Online-Zugang: DOAB: download the publication; DOAB: description of the publication

Marine habitats are promising sources to identify novel organisms and compounds. A total of 70% of the planet's surface is covered by ocean, and little is known about the biosphere within these habitats. In the last few years, numerous novel bioactive compounds or secondary metabolites from mar...