The Advances and Applications of Optogenetics

• Other Authors: Govorunova, Elena G. (Editor), Sineshchekov, Oleg A. (Editor)
• Format: Electronic Book Chapter
• Language: English
• Published: Basel, Switzerland MDPI - Multidisciplinary Digital Publishing Institute 2020
• Subjects: Research & information: general; Biology, life sciences; optogenetic tools; neuroscience; calcium sensor; voltage sensor; neurotransmitters; optogenetics; channelrhodopsins; sodium; calcium; DC gate; Optogenetics; p53; AsLOV2; LINuS; LEXY; MIP; PMI; Chlamydomonas reinhardtii; ion channel; electrophysiology; molecular dynamics simulations; membrane-protein interaction; energy of membrane deformation; CTMD method, residual hydrophobic mismatch; microbial rhodopsin; channelrhodopsin; membrane current; hippocampal neurons; light stimulation; channelrhodopsin-2; photoreceptor; BLUF; modular domain; resonance Raman; flash photolysis; hybrid QM/MM simulation; two-photon; azobenzene; photoswitch; photoswitching; photocontrol; all-optical electrophysiology; microbial rhodopsins; ion channels; LOV domains; membrane potential; intracellular trafficking; protein-protein interaction; signaling
• Online Access: DOAB: download the publication; DOAB: description of the publication

This book provides an update for the rapidly developing technology known as "optogenetics", which is the use of genetically encoded light-sensitive molecular elements (usually derived from lower organisms) to control or report various physiological and biochemical processes within the cell...