Updates on Osteoimmunology: What's New on the Crosstalk Between Bone and Immune Cells

In the last twenty years, different discoveries have emphasized the cross-talk between bone and immune cells as well as their common regulatory pathways. Indeed, soluble molecules produced by immune cells modulate the behavior of osteoblasts and osteoclasts. Moreover, osteoclasts, the bone-resorbing...

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Other Authors: Brunetti, Giacomina (Editor), D'Amelio, Patrizia (Editor), Mori, Giorgio (Editor), Felicia Faienza, Maria (Editor)
Format: Electronic Book Chapter
Language:English
Published: Frontiers Media SA 2020
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Summary:In the last twenty years, different discoveries have emphasized the cross-talk between bone and immune cells as well as their common regulatory pathways. Indeed, soluble molecules produced by immune cells modulate the behavior of osteoblasts and osteoclasts. Moreover, osteoclasts, the bone-resorbing cells, originate from the same myeloid precursor cells that differentiated into macrophages and myeloid dendritic cells. Whereas, the bone-forming osteoblastic cells control hematopoietic stem cell niches and thus immune cell ontology. The amplified recognition of the complex relationship between the immune system and bone led to the designation of osteoimmunology field. This Research Topic collects articles that highlight the cross-talk between bone and immune cells,
Physical Description:1 electronic resource (170 p.)
ISBN:978-2-88963-613-6
9782889636136
Access:Open Access