Fungal Infections Complicating COVID-19

• Other Authors: Hoenigl, Martin (Editor), Talento, Alida Fe (Editor)
• Format: Electronic Book Chapter
• Language: English
• Published: Basel, Switzerland MDPI - Multidisciplinary Digital Publishing Institute 2021
• Subjects: Medicine; SARS-CoV-2; co-infection; pulmonary aspergillosis; ICU; azole-resistant Aspergillus; Aspergillus fumigatus; CAPA; TR34L98H; SARS COV-2; Aspergillus; novel coronavirus; superinfection; risk factors; prevalence; challenges; immune response; expert statement; European Confederation of Medical Mycology; COVID-19; fungaemia; Saccharomyces; co-infections; invasive aspergillosis; putative; probable; Sars-CoV-2; PCR; galactomannan; classification; COVID-19 pneumonia; invasive pulmonary aspergillosis; diagnosis; multi-triazole resistance; COVID-19 associated invasive pulmonary aspergillosis; coinfection; diabetes; bloodstream infection; Candida glabrata; echinocandin resistance; FKS mutation; candidemia; candiduria; oral candidiasis; mycobiome; n/a
• Online Access: DOAB: download the publication; DOAB: description of the publication

Coronavirus disease 2019 (COVID-19), caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), spread globally to pandemic proportions. Although the majority of cases have asymptomatic or mild infections, a significant proportion of cases progress to severe pneumonia and acute respiratory distress syndrome requiring critical care. Opportunistic infections following severe respiratory viral infections have been recognized since the 1918 influenza pandemic. Among critically ill patients with COVID-19, secondary fungal infections caused by Aspergillus and Candida spp. are increasingly described, affecting up to 30% of COVID-19 patients requiring intensive care treatment. This collection of manuscripts focuses on fungal infections complicating COVID-19, including immunological mechanisms and pathogenesis, diagnosis, and treatment.