Ubiquitin and Autophagy

• Other Authors: Nazarko, Taras Y. (Editor)
• Format: Electronic Book Chapter
• Language: English
• Published: Basel, Switzerland MDPI - Multidisciplinary Digital Publishing Institute 2021
• Subjects: Research & information: general; Biology, life sciences; PSMD14; ubiquitin; retrograde; trafficking; APP; autophagy; Cx43; GABARAP; gap junction; MAPLC3; leukodystrophies; globoid cell leukodystrophy; psychosine; p62; proteasome; toll-like receptor 4; TRAF6; BECN1; ATG12~5/16 complex; Dictyostelium; ubiquitin-like protein; phagocytosis; pinocytosis; UPS; ubiquitin-proteasome system; crosstalk; tissue specificity; C. elegans; NFAT5; autophagy initiation; islet; FIP200; unfolded protein response; UPR; Atg8; LC3; LIR motif; SAR; UBL; neurodegenerative diseases; autophagy-lysosome pathway; lysosome; selective autophagy; ubiquitination; degradation; the ubiquitin-proteasome system; plants; mitophagy; aggrephagy; lysophagy; xenophagy; lipophagy; nucleophagy; ER-phagy; cargo receptors; sorting nexins; retromer; endosome; n/a
• Online Access: DOAB: download the publication; DOAB: description of the publication

This book is a collection of articles from the Cells Special Issue on "Ubiquitin and Autophagy". It contains an Editorial and 13 articles at the intersection of ubiquitin- and autophagy-related processes. Ubiquitin is a small protein modifier that is widely used to tag proteins, organelles, and pathogens for their degradation by the ubiquitin-proteasome system and/or autophagy-lysosomal pathway. Interestingly, several ubiquitin-like proteins are at a core of the autophagy mechanism. This book dedicates a lot of attention to the crosstalk between the ubiquitin-proteasome system and autophagy and serves as a good starting point for the readers interested in the current state of the knowledge on ubiquitin and autophagy.