EmbryoGenetics

• Andre forfattere: Simón, Carlos (Editor), Rubio, Carmen (Editor)
• Format: Electronisk Book Chapter
• Sprog: engelsk
• Udgivet: Basel, Switzerland MDPI - Multidisciplinary Digital Publishing Institute 2021
• Fag: Research & information: general; extracellular vesicles; exosomes; microvesicles; apoptotic bodies; DNA; preimplantation embryos; murine blastocysts; embryo; uterus; window of implantation; PGT-A; PGT-SR; mosaicism; embryo genetics; chromosomal abnormality; preimplantation genetic testing; PGT-P; polygenic risk scoring; genomic index; relative risk reduction; combined preimplantation genetic testing; Preimplantation genetic testing for monogenic disorders (PGT-M); Preimplantation genetic testing for aneuploidy assessment (PGT-A); Autosomal dominant polycystic kidney disease (ADPKD); male infertility; advanced maternal age; aneuploidy; NGS; segmental; translocations; monogenic disease; multiplex PCR; SNP array; genome editing; genetic diseases; embryos; vitrification; ovarian response; female age; genetic testing; reproductive health; next-generation sequencing; whole exome sequencing; perinatal care; infertility; aneuploidies; polygenic disease; blastocyst; endometrium; implantation
• Online adgang: DOAB: download the publication; DOAB: description of the publication

The science of human genetics has advanced at an exponential pace since the double-helix structure of DNA was identified in 1953. Within only 25 years of that discovery, the first gene was sequenced. Subsequent efforts in the span of a few decades have brought advanced next-generation sequencing and...