Preclinical Evaluation of Lipid-Based Nanosystems

• Other Authors: Silva, Ana Catarina (Editor), Sousa Lobo, José Manuel (Editor)
• Format: Electronic Book Chapter
• Language: English
• Published: Basel, Switzerland MDPI - Multidisciplinary Digital Publishing Institute 2021
• Subjects: Technology: general issues; nanostructured lipid carriers (NLC); formulation optimization; rivastigmine; quality by design (QbD); nasal route; nose-to-brain; N-alkylisatin; liposome; urokinase plasminogen activator; PAI-2; SerpinB2; breast cancer; liposomes; target delivery nanosystem; FZD10 protein; colon cancer therapy; supersaturation; silica-lipid hybrid; spray drying; lipolysis; lipid-based formulation; fenofibrate; mesoporous silica; oral drug delivery; hyaluronic acid; drug release; light activation; stability; mobility; biocorona; dissolution enhancement; phospholipids; solid dosage forms; porous microparticles; nanoemulsion(s); phase-behavior; DoE; D-optimal design; vegetable oils; non-ionic surfactants; efavirenz; flaxseed oil; nanostructured lipid carriers; nanocarrier; docohexaenoic acid; neuroprotection; neuroinflammation; fluconazole; Box‒Behnken design; nanotransfersome; ulcer index; zone of inhibition; rheological behavior; ex vivo permeation; nanomedicine; cancer; doxorubicin; melanoma; drug delivery; ultrasound contrast agents; phospholipid coating; ligand distribution; cholesterol; acoustic response; microbubble; lipid phase; dialysis; ammonia; intoxication; cyanocobalamin; vitamin B12; atopic dermatitis; psoriasis; transferosomes; lipid vesicles; skin topical delivery; oligonucleotide; self-emulsifying drug delivery systems; hydrophobic ion pairing; intestinal permeation enhancers; Caco-2 monolayer; clarithromycin; solid lipid nanoparticles; optimization; permeation; pharmacokinetics; follicular targeting; dexamethasone; alopecia areata; lipomers; lipid polymer hybrid nanocapsules; biodistribution; skin; ethyl cellulose; n/a
• Online Access: DOAB: download the publication; DOAB: description of the publication

The use of lipid-based nanosystems, including lipid nanoparticles (solid lipid nanoparticles (SLN) and nanostructured lipid carriers (NLC)), nanoemulsions, and liposomes, among others, is widespread. Several researchers have described the advantages of different applications of these nanosystems. Fo...