Mitochondria: From Physiology to Pathology

• Other Authors: Bruni, Francesco (Editor)
• Format: Electronic Book Chapter
• Language: English
• Published: Basel, Switzerland MDPI - Multidisciplinary Digital Publishing Institute 2021
• Subjects: Research & information: general; atherosclerosis; carotid intima-media thickness; mitochondrial mutations; cardiovascular risk factors; mitochondria; mtDNA; cristae; mitochondrial fission; mitochondrial fusion; mitochondrial diseas; mitochondrial dynamics; mitoenergetics; mitosteroidogenesis; LH; cAMP; Leydig cell; mitochondrial DNA segregation; heteroplasmy; selective elimination; mitophagy; mitochondrial engineered nucleases; kinases; phosphorylation; disease; PINK1; Parkinson's disease; mitochondria homeostasis; Cterm; MELAS; transmitochondrial cybrids; aminoacyl-tRNA synthetases; LARS2; mitochondrial disease; therapeutic peptides; FAD synthase; FAD1; mitochondria localization; Saccharomyces cerevisiae; mRNA; mitochondrial localization motif; n/a
• Online Access: DOAB: download the publication; DOAB: description of the publication

Mitochondria play an increasingly central role in the context of cellular physiology. These organelles possess their own genome (mtDNA), which is functionally coordinated with the nuclear genome. Mitochondrial gene expression is mediated by molecular processes (replication, transcription, translatio...