Extracellular Vesicles: Biology and Potentials in Cancer Therapeutics

• Other Authors: Cho, William (Editor)
• Format: Electronic Book Chapter
• Language: English
• Published: Basel, Switzerland MDPI - Multidisciplinary Digital Publishing Institute 2021
• Subjects: Medicine; extracellular vesicle; precision oncology; cancer biomarker; prostate cancer; drug delivery; extracellular vesicles; lysosome; nanocarriers; ultrasound; size exclusion chromatography; differential ultracentrifugation; head and neck squamous cell carcinoma (HNSCC); exosomes; cancer; biomarker; diagnostic; therapy; liquid biopsy; small extracellular vesicles (sEV); tumor-derived exosomes (TEX); melanoma cell-derived exosomes (MTEX); proteomics; tumor microenvironment; biomarkers; ectosomes; neoplasia; microvesicles; small extracellular vesicles; isolation; purification; size-exclusion chromatography; ultracentrifugation; sucrose density cushion; lymph node; spleen; solid tissue; microvesicle; exosome; cancer therapeutic; drug carrier; flow cytometry; immunophenotyping; swarm detection; tumor-associated macrophages; macrophage polarization; mannose receptor; HIV-1 Nef; glioblastoma; microRNA; immunoprecipitation; CD44; human milk; nutrient; microbiota; microRNAs; nanocommunicator; diagnostic biomarker; drug delivery vehicle; personalized cancer immunotherapy; therapeutic agents; cell-to-cell communication; ionising radiation; non-targeted effects; signalling; imaging flow cytometry; biomarker reservoirs; cancer diagnostics; disease monitoring; large EVs; ovarian cancer cells; ES-2; OAW-42; adipose tissue origin mesenchymal stem cells; n/a
• Online Access: DOAB: download the publication; DOAB: description of the publication

Extracellular vesicles (EVs) are particles wrapped in a lipid bilayer membrane and are naturally released from cells. This kind of cargo vessel is a nanostructure that mainly transfers lipids, proteins, various nucleic acid fragments, and metabolic components to neighboring cells or distant parts of...