Nucleic Acids Conjugates for Biotechnological Applications

• Other Authors: Endoh, Tamaki (Editor), Rozners, Eriks (Editor), Ohtsuki, Takashi (Editor)
• Format: Electronic Book Chapter
• Language: English
• Published: Basel, Switzerland MDPI - Multidisciplinary Digital Publishing Institute 2021
• Subjects: Technology: general issues; fluorescent probe; conjugate; abasic site; DNA; microRNA; RNA binding protein; PUF; RNA regulation; DNA-protein conjugate; replication initiation protein; DNA aptamer; BRET-based biosensor; oligonucleotide; crosslink; nucleic acid binding protein; cytosine methyltransferase; mRNA; poly(A) tail; artificial viral capsid; encapsulation; nanocapsule; self-assembly; β-annulus peptide; peptide-DNA conjugate; PNA; invasion; NLS; drug delivery system; anticancer drug; camptothecin derivative; irinotecan; ribonucleopeptide (RNP); RNA-peptide conjugate; Schiff base; aptamer; fluorescent sensors; therapeutic nucleic acid; drug delivery; nanoparticles; cytotoxicity; macrophages; cellular uptake; small interfering RNA; multiple sclerosis; repulsive guidance molecule a; catalytic RNA; group I ribozyme; RNA nanostructure; RNA nanotechnology; RNA-protein complex; trans-splicing; n/a
• Online Access: DOAB: download the publication; DOAB: description of the publication

Life in biological systems is maintained by the cooperative actions of various biomolecules. With the development of chemical and biological technologies related to nucleic acids, the details of the mechanisms of such cooperative actions between nucleic acids and other biomolecules have been elucidated and further applied in various applications. In the papers published in this Special Issue, advanced research works involved in nucleic acid conjugates are reported in wide application fields, such as artificial gene regulation, biomolecular sensing, and therapeutics from leading scientists in nucleic acids chemistry and engineering.