Extension of Healthy Life Span of Dialysis Patients in the Era of a 100-Year Life

Malnutrition is becoming a more prominent health problem, with an increasing number of elderly CKD patients being put on dialysis. In addition, the presence of inflammation, sarcopenia/frailty, diabetes, and CVD is a definite and independent risk factor associated with higher mortality in this popul...

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Other Authors: Inaba, Masaaki (Editor), Mori, Katsuhiko (Editor)
Format: Electronic Book Chapter
Language:English
Published: Basel, Switzerland MDPI - Multidisciplinary Digital Publishing Institute 2021
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520 |a Malnutrition is becoming a more prominent health problem, with an increasing number of elderly CKD patients being put on dialysis. In addition, the presence of inflammation, sarcopenia/frailty, diabetes, and CVD is a definite and independent risk factor associated with higher mortality in this population. Although the restriction of protein intake has been recommended to protect eGFR decline, hyperphosphatemia, and hyperkalemia in CKD patients, it might accelerate the loss of skeletal muscle and adipose mass, leading to a poor prognosis. Therefore, flexible responses are considered regarding whether protein restriction should be continued or loosened in pre-dialysis CKD patients. In undernourished elderly patients undergoing hemodialysis, sufficient calorie/protein intake is necessary to counteract the development of sarcopenia/frailty. It is expected that the application of new drugs including phosphate binders and potassium chelators may achieve both a high enough intake and balanced levels of phosphate and potassium. Furthermore, the improvement of deficient micronutrients and poor appetite is also necessary. Comprehensive care is essential for the wellbeing of elderly patients undergoing hemodialysis. The topicof this Special Issue is "Extension of Healthy Life Span of Dialysis Patients in the Era of a 100-Year Life". 
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650 7 |a Medicine  |2 bicssc 
653 |a hypertension 
653 |a body weight 
653 |a mortality 
653 |a sodium 
653 |a dialysis 
653 |a malnutrition 
653 |a protein energy wasting (PEW) 
653 |a sarcopenia 
653 |a carnitine 
653 |a carnitine deficiency 
653 |a end-stage kidney disease 
653 |a peritoneal dialysis 
653 |a hemodialysis 
653 |a frailty 
653 |a protein energy wasting 
653 |a hypercatabolism 
653 |a renal rehabilitation 
653 |a exercise 
653 |a sarcopenia and frailty 
653 |a nutritional support 
653 |a protein synthesis 
653 |a muscle physiology 
653 |a physical activity 
653 |a exercise tolerance 
653 |a quality of life 
653 |a skeletal muscle 
653 |a aging 
653 |a chronic kidney disease 
653 |a diabetes 
653 |a CKD-MBD 
653 |a FGF23 
653 |a aKlotho 
653 |a phosphate-binder 
653 |a zinc 
653 |a cardiovascular disease 
653 |a potassium 
653 |a potassium excretion 
653 |a blood pressure 
653 |a salt 
653 |a CKD 
653 |a fat mass 
653 |a visceral fat 
653 |a subcutaneous fat 
653 |a nutrition 
653 |a body mass index 
653 |a obesity paradox 
653 |a magnetic resonance imaging 
653 |a diffusion tensor imaging 
653 |a arterial spin labeling 
653 |a blood oxygenation level-dependent 
653 |a nutritional status 
653 |a dialysis patients 
653 |a clinical malnutrition 
653 |a older individuals 
653 |a n/a 
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