Advanced Therapy Medicinal Products for Eye Diseases: Goals and Challenges

• Other Authors: Diebold, Yolanda (Editor), García-Posadas, Laura (Editor)
• Format: Electronic Book Chapter
• Language: English
• Published: Basel, Switzerland MDPI - Multidisciplinary Digital Publishing Institute 2021
• Subjects: Medicine; MPC polymer; dry eye; ocular surface; lacrimal fluid; mucin; 3D bioprinting; cornea; retina; ophthalmology; tissue regeneration; electrospinning; conjunctiva; decellularized tissue matrix; small intestinal submucosa; urinary bladder matrix; polycaprolactone; fiber; tissue engineering; stratification; conjunctival epithelial cells; hydrogel; keratoplasty; scaffold; collagen; advanced therapy medicinal product; ATMP; cell therapy; gene therapy; eye; ocular; regulatory; marketing authorization; double-crosslinking; carbodiimide; glutaraldehyde; sodium metabisulfite; sodium borohydride; EDC/NHS; stem cells; retinal diseases; optic nerve diseases; cell replacement; cell sources; advanced therapies; ocular mucosa; blindness; CLET; limbal niche; limbal stem cell; LSCD; mesenchymal stem cell transplantation; MSCT; corneal limbus; decellularized xenograft; recellularization; mesenchymal stem cells; n/a
• Online Access: DOAB: download the publication; DOAB: description of the publication

The concept of advanced therapy medicinal products (ATMPs) encompasses novel kinds of medicines for human use that are based on genes, cells or tissues. These intend to offer not only regeneration, but complete functional recovery of diseased tissues and organs using different strategies. Gene thera...