Hypoxia-Inducible Factors Regulation and Therapeutic Potential

• Other Authors: Hirota, Kiichi (Editor)
• Format: Electronic Book Chapter
• Language: English
• Published: Basel MDPI - Multidisciplinary Digital Publishing Institute 2022
• Subjects: Medicine; hypoxia; transcriptome; RNA-seq; ChIP-seq; public database; meta-analysis; peripheral blood cells; blood-derived therapy; angiogenesis; platelet rich plasma (PRP); hypoxia preconditioned plasma; hypoxia preconditioned serum; transcription factor; hypoxia-inducible factor 1; HIF-1; hypoxia sensing; acetylsalicylic acid; COX-1; clopidogrel; drug anticoagulation; NOACs; oral anticoagulation; VEGF; adipose-derived stem cells; adipose-derived cell supension; lymphangiogenesis; lymphatic regeneration; macrophage; matrix metalloproteinase; atherosclerotic plaque rupture; oxidative stress; xanthine oxidase; HIF; T cells; B cells; monocytes; macrophages; neutrophils; ILC; oxygen; HIF-PH inhibitor; gene2pubmed; bibliome; signature genes; GPR146; enrichment analysis; n/a
• Online Access: DOAB: download the publication; DOAB: description of the publication

Oxygen is an essential molecule in the production of adenosine triphosphate (ATP) in cells, and a lack of energy due to O2 deficiency makes the maintenance of biological functions and human life improbable. Since oxygen functions as the final electron acceptor in the series of ATP synthesis reaction...