Personalized Medicine in Oncology

• Andere auteurs: VanderWalde, Ari (Redacteur)
• Formaat: Elektronisch Hoofdstuk
• Taal: Engels
• Gepubliceerd in: Basel MDPI - Multidisciplinary Digital Publishing Institute 2022
• Onderwerpen: Medicine; patient-derived tumor xenograft (PDX); anti-cancer drug development; immunodeficient mice; precision medicine; molecular profiling; immunohistochemistry; next-generation sequencing; targeted therapy; molecular oncology; biomarkers; molecular imaging; non-small cell lung cancer; proliferation; cancer stem cells; circulating tumour cells; personalised treatment; renal cell carcinoma; clear cell; VEGF; immunotherapy; PD-L1; immune checkpoint inhibitors; immune checkpoint blockade; tyrosine-kinase inhibitors; integrin-linked kinase (ILK); ovarian cancer; sgRNA; gene expression; microarray; xenograft; MTB; cancer; oncology practice; community setting; CGP; pancreatic cancer; FOLFIRINOX; chemotherapy; gender; cholangiocarcinoma; biliary tract cancer; prognosis; neutrophils; BRCA1; BRCA2; PALB2; homologous recombination repair; colorectal cancer; heme oxygenase-1; endothelin-1; endothelin con-verting enzyme-1; bosentan; precision oncology; tumor-agnostic indications; solid tumors; tumor markers; FDA-approved therapeutics; n/a
• Online toegang: DOAB: download the publication; DOAB: description of the publication

Nowhere is the explosion in comprehensive genomic testing more evident than in oncology. Multiple consensus guidelines now recommend molecular testing as the standard of care for most metastatic tumors. To aid in the advancement of this rapidly changing field, we intend this Special Issue of JPM to...