Therapeutic Monoclonal Antibodies and Antibody Products, Their Optimization and Drug Design in Cancers

The book broadly deals with therapeutic monoclonal antibodies (mAbs) and various relevant topics, including different antibody formats such as Antibody-Drug Conjugates (ADC), bispecifics, nanoparticle-based mAbs and HER2+ cancers, immune checkpoint inhibitors and other closely related topics. Each p...

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Bibliographic Details
Other Authors: Kayser, Veysel (Editor)
Format: Electronic Book Chapter
Language:English
Published: Basel MDPI - Multidisciplinary Digital Publishing Institute 2022
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Online Access:DOAB: download the publication
DOAB: description of the publication
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520 |a The book broadly deals with therapeutic monoclonal antibodies (mAbs) and various relevant topics, including different antibody formats such as Antibody-Drug Conjugates (ADC), bispecifics, nanoparticle-based mAbs and HER2+ cancers, immune checkpoint inhibitors and other closely related topics. Each paper was written by leading active research groups in their fields both from academia and industry. The book should be of interest to those scientists and researchers who develop or use biologics, biotherapeutics, biosimilars and biobetters in cancer treatment. 
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653 |a monoclonal antibody 
653 |a NSCLC 
653 |a immunotherapy 
653 |a ELISA 
653 |a pharmacokinetics 
653 |a pharmacogenetics 
653 |a anti-PD-1 monoclonal antibodies 
653 |a anti-acetylcholine receptor (AChR) antibody 
653 |a B cell 
653 |a immune checkpoint blockade 
653 |a immune-related adverse events (irAEs) 
653 |a myasthenia gravis (MG) 
653 |a non-small-cell lung cancer (NSCLC) 
653 |a nivolumab 
653 |a programmed cell death ligand 1 (PD-L1) 
653 |a T cell 
653 |a tetraspanins 
653 |a cancer 
653 |a Tspan8 
653 |a radioimmunotherapy 
653 |a immune-checkpoint inhibitors 
653 |a LDH 
653 |a biomarkers 
653 |a Ang-2 
653 |a antiangiogenic therapy 
653 |a in vivo imaging 
653 |a radio- and chemotherapy 
653 |a VEGF-A 
653 |a cancer therapy 
653 |a neovascularization 
653 |a angiogenesis 
653 |a tumor microenvironment 
653 |a colorectal cancer 
653 |a antibody 
653 |a NK cells 
653 |a ADCC 
653 |a CD133 
653 |a prominin-1 
653 |a gold nanoparticles 
653 |a antibody-drug conjugates 
653 |a cell penetrating peptide 
653 |a HIV-1 TAT 
653 |a active-targeting 
653 |a targeted delivery 
653 |a trastuzumab 
653 |a MMAE 
653 |a valine-citrulline 
653 |a affibody 
653 |a drug conjugates 
653 |a hepatic uptake 
653 |a DM1 
653 |a dermatooncology 
653 |a immune checkpoints 
653 |a monoclonal antibodies 
653 |a passive immunotherapy 
653 |a canine B-cell lymphoma 
653 |a DLA-DR 
653 |a HLA-DR 
653 |a antibody-drug conjugate 
653 |a ADC 
653 |a methotrexate 
653 |a tumor immunity 
653 |a combination therapy 
653 |a multiple myeloma (MM) 
653 |a monoclonal antibodies (mAbs) 
653 |a antibody products 
653 |a B cell maturation antigens (BCMAs) 
653 |a bispecific T cell engagers (BiTEs®) 
653 |a checkpoint inhibitors 1 
653 |a protein structure 2 
653 |a pharmacokinetics 3 
653 |a drug optimization 4 
653 |a HER2-positive breast cancer 
653 |a metastatic disease 
653 |a neoadjuvant and adjuvant therapy 
653 |a targeted therapy 
653 |a acute myeloid leukemia 
653 |a CD123 
653 |a IL3RA 
653 |a kinesin spindle protein inhibitor 
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856 4 0 |a www.oapen.org  |u https://directory.doabooks.org/handle/20.500.12854/78803  |7 0  |z DOAB: description of the publication