O-GlcNAcylation and Cancer

O-GlcNAcylation and Cancer

This book gathers reviews and articles on the role of O-GlcNAcylation in cancer underlying the pharmacological targeting of the O-GlcNAcylation enzymes OGT and OGA as a promising anticancer strategy. Particular attention is paid to the involvement of O-GlcNAcylation in the regulation of transcriptio...

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Bibliographic Details
Other Authors: El Yazidi-Belkoura, Ikram (Editor), Lefebvre, Tony (Editor)
Format: Electronic Book Chapter
Language:English
Published: Basel MDPI - Multidisciplinary Digital Publishing Institute 2022
Subjects:
Research & information: general
UNC5A
O-GlcNAcylation
OGT
EZH2
nutrition
epigenetics
colon cancer
transcription
O-GlcNAc
O-GlcNAc transferase
O-GlcNAcase
mOGT
mitochondria
glucose
energy metabolism
breast cancer
cellular stress
cancer
immune surveillance
invasiveness
lung adenocarcinoma
SAM68
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Description
Summary:This book gathers reviews and articles on the role of O-GlcNAcylation in cancer underlying the pharmacological targeting of the O-GlcNAcylation enzymes OGT and OGA as a promising anticancer strategy. Particular attention is paid to the involvement of O-GlcNAcylation in the regulation of transcription and as a link between nutrition and epigenetic dynamics or cellular energy metabolism. The role of O-GlcNAcylation in metastasis, immune responses, and resistance to chemotherapeutic agents is also discussed.
Physical Description:1 electronic resource (112 p.)
ISBN:books978-3-0365-3082-6
9783036530826
9783036530833
Access:Open Access

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