O-GlcNAcylation and Cancer

This book gathers reviews and articles on the role of O-GlcNAcylation in cancer underlying the pharmacological targeting of the O-GlcNAcylation enzymes OGT and OGA as a promising anticancer strategy. Particular attention is paid to the involvement of O-GlcNAcylation in the regulation of transcriptio...

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Bibliographic Details
Other Authors: El Yazidi-Belkoura, Ikram (Editor), Lefebvre, Tony (Editor)
Format: Electronic Book Chapter
Language:English
Published: Basel MDPI - Multidisciplinary Digital Publishing Institute 2022
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DOAB: description of the publication
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520 |a This book gathers reviews and articles on the role of O-GlcNAcylation in cancer underlying the pharmacological targeting of the O-GlcNAcylation enzymes OGT and OGA as a promising anticancer strategy. Particular attention is paid to the involvement of O-GlcNAcylation in the regulation of transcription and as a link between nutrition and epigenetic dynamics or cellular energy metabolism. The role of O-GlcNAcylation in metastasis, immune responses, and resistance to chemotherapeutic agents is also discussed. 
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653 |a lung adenocarcinoma 
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