O-GlcNAcylation and Cancer

• Other Authors: El Yazidi-Belkoura, Ikram (Editor), Lefebvre, Tony (Editor)
• Format: Electronic Book Chapter
• Language: English
• Published: Basel MDPI - Multidisciplinary Digital Publishing Institute 2022
• Subjects: Research & information: general; UNC5A; O-GlcNAcylation; OGT; EZH2; nutrition; epigenetics; colon cancer; transcription; O-GlcNAc; O-GlcNAc transferase; O-GlcNAcase; mOGT; mitochondria; glucose; energy metabolism; breast cancer; cellular stress; cancer; immune surveillance; invasiveness; lung adenocarcinoma; SAM68
• Online Access: DOAB: download the publication; DOAB: description of the publication

This book gathers reviews and articles on the role of O-GlcNAcylation in cancer underlying the pharmacological targeting of the O-GlcNAcylation enzymes OGT and OGA as a promising anticancer strategy. Particular attention is paid to the involvement of O-GlcNAcylation in the regulation of transcriptio...