Oligonucleotide, Therapy, and Applications

• Outros Autores: Aliño, Salvador (Editor), Sendra, Luis (Editor)
• Formato: Recurso Electrónico Capítulo de Livro
• Idioma: inglês
• Publicado em: Basel MDPI - Multidisciplinary Digital Publishing Institute 2022
• Assuntos: Medicine; quantum dots (QDs); DNAzyme; ROS; Amplex Red; light-induced activity; DNA methylation; histone code; microRNA; nanoparticles; noncoding RNA; pulmonary arterial hypertension; aptamer; aptasensor; influenza; SERS; virus detection; α-synuclein; antisense oligonucleotide; dopamine neurotransmission; double mutant A30P*A53T*; motor deficits; Parkinson's disease; transgenic mouse model; G-quadruplexes; covalent dimer construct; anti-proliferative activity; primary cell culture of human glioma; antisensense oligonucleotide; Foxp3; regulatory T cells; vaccine immunogenicity; Sporothrix schenckii; Marfan syndrome; fibrillin-1; antisense oligonucleotides; exon skipping; splice-switching
• Acesso em linha: DOAB: download the publication; DOAB: description of the publication

Oligonucleotides (ON) constitute a new group of molecular agents, the object of significant interest due to their potential value as drugs for diagnostic and therapeutic applications. Their special interest derives from the intrinsic characteristics of ONs: a) ONs are informative agents, a property...