Monoclonal Antibodies and Their Functional Fragments in Research, Diagnosis and Therapy

• Other Authors: Ruvo, Menotti (Editor)
• Format: Electronic Book Chapter
• Language: English
• Published: Basel MDPI - Multidisciplinary Digital Publishing Institute 2022
• Subjects: Technology: general issues; porcine deltacoronavirus; nucleocapsid; monoclonal antibodies; neurodegenerative disorders; affibody molecules; blood-brain barrier; receptor-mediated transcytosis; transferrin receptor; AL amyloidosis; CD38; anti-CD38 MoAb; Daratumumab; Isatuximab; myeloma; BCMA; bispecific T-cell engager; antibody-drug conjugates; chimeric antigen receptor T-cells; belantamab mafodotin; idecabtagene vicleucel; JNJ-68284528; Mabs; Antibody-Drug Conjugate; cancer therapy; drug targeting; payload; cross-linking; antibody fragment; Fab; scFv; E. coli; YKL-40; CHI3L1; monoclonal antibody; phage display; lung metastasis; prostate-specific membrane antigen; in vivo imaging; prostate cancer; glutamate carboxypeptidase II; NAALADase; immunization; antibody; protocol; guinea pig; cDNA; chimeric antigen receptor (CAR T); universal CAR T; modular CAR T; universal immune receptor; CAR adaptor; adoptive immunotherapy; split CAR; bispecific; polyspecificity; pharmacokinetics; solubility; aggregation; viscosity; developability; stability; affinity; specificity; protein engineering; self-association; non-specific binding; immunogenicity; antibody fragments; single chain; amyloid; oligomer; neurotoxicity; NUsc1
• Online Access: DOAB: download the publication; DOAB: description of the publication

Summary

This book is a compendium of scientific articles submitted to a Special Issue of International Journal of Molecular Sciences, fostered by MDPI and curated by Dr. Annamaria Sandomenico and Dr. Menotti Ruvo from the Institute of Biostructure and Bioimaging of the National Research Council. All articles underwent a rigorous peer review and were selected to highlight the properties that make monoclonal antibodies and their functional fragments some of the most useful and versatile assets in therapy and diagnosis.

Physical Description

1 electronic resource (278 p.)

ISBN

books978-3-0365-3166-3
9783036531670
9783036531663

Access

Open Access