Natural Product from the Deep Sea

• Andere auteurs: Umezawa, Kazuo (Redacteur)
• Formaat: Elektronisch Hoofdstuk
• Taal: Engels
• Gepubliceerd in: Basel MDPI - Multidisciplinary Digital Publishing Institute 2022
• Onderwerpen: Medicine; deep sea marine-derived fungus; Myrothecium sp.; myrothecol; nitric oxide (NO); antioxidant activity; macrolactam; Deep-Sea-Derived Streptomyces; abiotic formation; natural product; antifungal activity; Thorectandra choanoides; tryptophan alkaloid; indoleamine 2,3-dioxygenase; aplysinopsins; GNPS molecular network; cellular signal transduction; bioactive metabolite; deep-sea organisms; anti-inflammatory agent; anticancer agent; Mariana Trench; Micromonospora provocatoris MT25; desferrioxamine; n-acetylglutaminyl glutamine amide; 1H-15N 2D-NMR; genomics; biosynthetic gene clusters; stress genes; crustins; antibacterial peptides; hydrothermal vent; anti-Gram-negative bacteria; Al-crus 3 and Al-crus 7; Trichoderma; harziane diterpenes; NO inhibition; thioester-containing benzoate; deep-sea-derived fungus; α-glucosidase inhibitory activity; docking study
• Online toegang: DOAB: download the publication; DOAB: description of the publication

After the long history of screening, it is becoming difficult to find novel compounds from microorganisms and plants anywhere in the world. Until now, more than about 30,000 marine natural products have been reported. However, with the development of marine natural products research, the hit rate of...