Gastrointestinal Cancers and Personalized Medicine

Gastrointestinal cancers, such as esophageal and gastric cancers, pancreatic cancers, hepatobiliary cancers, colorectal cancers and gastrointestinal stromal tumors, are frequently diagnosed at an advanced stage and have a dismal prognosis. Even in patients with potentially curative cancer, nearly 50...

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Bibliographic Details
Other Authors: Mini, Enrico (Editor), Nobili, Stefania (Editor)
Format: Electronic Book Chapter
Language:English
Published: Basel MDPI - Multidisciplinary Digital Publishing Institute 2022
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DOAB: description of the publication
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520 |a Gastrointestinal cancers, such as esophageal and gastric cancers, pancreatic cancers, hepatobiliary cancers, colorectal cancers and gastrointestinal stromal tumors, are frequently diagnosed at an advanced stage and have a dismal prognosis. Even in patients with potentially curative cancer, nearly 50\% will develop recurrent disease despite aggressive treatments. A number of biomarkers currently guide treatment decisions for patients with gastrointestinal neoplasms. Major technological advances in genomics have made it possible to identify critical genetic alterations in cancer, furthering oncology along the path to "personalized cancer medicine". Future research efforts will focus on the identification of new biomarkers, moving existing biomarkers into earlier lines of therapy and evaluating new combinations of existing biomarkers and therapies.The aim of this Special Issue is to provide an overview of exciting new research in the area of gastrointestinal tumors that may establish innovative personalized management and precision medicine modalities for individualized care. 
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653 |a neutrophil-to-lymphocyte ratio 
653 |a lymphocyte-to-monocyte ratio 
653 |a prognosis 
653 |a rectal cancer 
653 |a mesorectum 
653 |a sphincter preserving 
653 |a molecular oncology 
653 |a precision medicine 
653 |a colorectal cancer 
653 |a targeted therapy 
653 |a molecular profiling 
653 |a pancreatic cysts 
653 |a thermal liquid biopsy 
653 |a differential scanning calorimetry 
653 |a diagnosis 
653 |a generalized linear models 
653 |a gene signature 
653 |a mRNA expression 
653 |a VANGL1 
653 |a FFPE 
653 |a neurotoxicity 
653 |a oxaliplatin 
653 |a chemotherapy-induced peripheral neuropathy 
653 |a biomarker 
653 |a genomics 
653 |a neuropathy 
653 |a FOLFOX 
653 |a FOLFIRINOX 
653 |a XELOX 
653 |a gastrointestinal cancer 
653 |a LAG-3 
653 |a immune checkpoint 
653 |a colon cancer 
653 |a survival 
653 |a microsatellite instability 
653 |a immunotherapy 
653 |a n/a 
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