Supramolecular Systems for Gene and Drug Delivery

• Other Authors: Ostos, Francisco José (Editor), Lebrón, José Antonio (Editor), López-Cornejo, Pilar (Editor)
• Format: Electronic Book Chapter
• Language: English
• Published: Basel MDPI - Multidisciplinary Digital Publishing Institute 2022
• Subjects: Research & information: general; Chemistry; β-cyclodextrin-based nanosponge; phenylethylamine; 2-amino-4-(4-chlorophenyl)thiazole (AT); gold nanoparticles; carrier of therapeutic agents; ferritin; drug delivery; tumor targeting; half-life extension; PAMAM dendrimers; folic acid; mRNA; gene expression; long acting injectables; poly(l-lactic acid); poly(butylene adipate); block copolymers; aripiprazole; microparticles; sustained release; cationic calix[4]arenes; liposomes; nucleic acids; transfection efficiency; doxorubicin; encapsulation; adenine-uracil base pair; complementary hydrogen bonded drug carrier system; controlled drug delivery; supramolecular nanogels; selective cytotoxicity; supramolecular self-assembled ribbon-like structures (SRLS); Congo red (CR); doxorubicin (Dox); bovine serum albumin (BSA); immunoglobulin light chain λ (Lλ); heat aggregated immunoglobulins (HAI); dynamic light scattering (DLS); elution volume (Ve); multi-walled carbon nanotube; photothermal therapy; indocyanine green; synergistic strategy; cancer treatment; targeted drug delivery; pillararene; host:guest; supramolecular; hydrophobic; ITC; NMR; magnetoliposomes; microfluidics; oral drug delivery; magnetite nanoparticles; n/a
• Online Access: DOAB: download the publication; DOAB: description of the publication

Dear Colleagues,Supramolecular systems (calixarenes, cyclodextrins, polymers, peptides, etc.) have attracted special attention due to their excellent therapeutic properties for biomedical applications such as gene and drug delivery. Numerous biomaterials-based supramolecular systems have been developed in the last decade for enhancing of biocompatibility and pharmacological activity. In particular, supramolecular nanomaterials are considered a hot research topic, because nanomedicine has become an interesting tool for the treatment of genetic diseases or cancer. Nevertheless, novel systems and their properties are being continuously studied, contributing to the development of efficient delivery systems.This Special Issue provides and highlights current progress in the use of the supramolecular systems for boosting gene and drug delivery. Preparation, characterization, and use of these systems, as well as the latest developments in this research field, are especially welcome.Authors are encorauged to submit original research articles and reviews in this promising research field.