Targeting Wnt Signaling in Cancer: Opportunities Abound If We Can Avoid the Sword of Damocles
Dysregulation of Wnt signaling is known to be associated with various cancers. As such, identification of novel Wnt pathway targets in cancer and better characterization of already-known targets present exciting, emerging opportunities for cancer treatment. In this Special Issue, we feature papers w...
Saved in:
| Other Authors: | , |
|---|---|
| Format: | Electronic Book Chapter |
| Language: | English |
| Published: |
Basel
MDPI - Multidisciplinary Digital Publishing Institute
2022
|
| Subjects: | |
| Online Access: | DOAB: download the publication DOAB: description of the publication |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
MARC
| LEADER | 00000naaaa2200000uu 4500 | ||
|---|---|---|---|
| 001 | doab_20_500_12854_81213 | ||
| 005 | 20220506 | ||
| 003 | oapen | ||
| 006 | m o d | ||
| 007 | cr|mn|---annan | ||
| 008 | 20220506s2022 xx |||||o ||| 0|eng d | ||
| 020 | |a books978-3-0365-3518-0 | ||
| 020 | |a 9783036535173 | ||
| 020 | |a 9783036535180 | ||
| 040 | |a oapen |c oapen | ||
| 024 | 7 | |a 10.3390/books978-3-0365-3518-0 |c doi | |
| 041 | 0 | |a eng | |
| 042 | |a dc | ||
| 072 | 7 | |a M |2 bicssc | |
| 072 | 7 | |a MMG |2 bicssc | |
| 100 | 1 | |a Kahn, Michael |4 edt | |
| 700 | 1 | |a Lai, Keane |4 edt | |
| 700 | 1 | |a Kahn, Michael |4 oth | |
| 700 | 1 | |a Lai, Keane |4 oth | |
| 245 | 1 | 0 | |a Targeting Wnt Signaling in Cancer: Opportunities Abound If We Can Avoid the Sword of Damocles |
| 260 | |a Basel |b MDPI - Multidisciplinary Digital Publishing Institute |c 2022 | ||
| 300 | |a 1 electronic resource (298 p.) | ||
| 336 | |a text |b txt |2 rdacontent | ||
| 337 | |a computer |b c |2 rdamedia | ||
| 338 | |a online resource |b cr |2 rdacarrier | ||
| 506 | 0 | |a Open Access |2 star |f Unrestricted online access | |
| 520 | |a Dysregulation of Wnt signaling is known to be associated with various cancers. As such, identification of novel Wnt pathway targets in cancer and better characterization of already-known targets present exciting, emerging opportunities for cancer treatment. In this Special Issue, we feature papers which discuss the role of Wnt signaling and associated targets in cancer metabolism, tumor immune response, and tumor microenvironment. Papers discussing a range of Wnt-mediated cancers, including those of the colon, liver, pancreas, synovium, bladder, etc., are included. | ||
| 540 | |a Creative Commons |f https://creativecommons.org/licenses/by/4.0/ |2 cc |4 https://creativecommons.org/licenses/by/4.0/ | ||
| 546 | |a English | ||
| 650 | 7 | |a Medicine |2 bicssc | |
| 650 | 7 | |a Pharmacology |2 bicssc | |
| 653 | |a Wnt signaling | ||
| 653 | |a synovial sarcoma | ||
| 653 | |a TNIK | ||
| 653 | |a NCB-0846 | ||
| 653 | |a MYC | ||
| 653 | |a hepatitis B virus | ||
| 653 | |a HBV | ||
| 653 | |a cancer | ||
| 653 | |a liver cancer | ||
| 653 | |a β-catenin | ||
| 653 | |a TCF/LEF | ||
| 653 | |a pancreatic cancer | ||
| 653 | |a pancreatic stellate cells | ||
| 653 | |a CBP | ||
| 653 | |a p300 | ||
| 653 | |a pancreatitis | ||
| 653 | |a fibrosis | ||
| 653 | |a just-right signaling | ||
| 653 | |a APC | ||
| 653 | |a colorectal cancer | ||
| 653 | |a RNA-binding proteins | ||
| 653 | |a Musashi | ||
| 653 | |a drug discovery | ||
| 653 | |a Notch signaling | ||
| 653 | |a cancer therapy | ||
| 653 | |a fungi secondary metabolite derivative | ||
| 653 | |a microenvironment | ||
| 653 | |a Wnt | ||
| 653 | |a AML | ||
| 653 | |a drug target | ||
| 653 | |a signaling | ||
| 653 | |a colorectal | ||
| 653 | |a porcupine | ||
| 653 | |a R-spondin | ||
| 653 | |a serrated | ||
| 653 | |a immunotherapy | ||
| 653 | |a wnt | ||
| 653 | |a vitamin D | ||
| 653 | |a colon cancer | ||
| 653 | |a L1 | ||
| 653 | |a Wnt target genes | ||
| 653 | |a cell adhesion | ||
| 653 | |a NF-κB | ||
| 653 | |a invasion and metastasis | ||
| 653 | |a cancer stem cells | ||
| 653 | |a EMT | ||
| 653 | |a Lgr5 | ||
| 653 | |a Wnt/beta-catenin signaling | ||
| 653 | |a angiogenesis | ||
| 653 | |a anti-angiogenic therapy | ||
| 653 | |a gastrointestinal cancers | ||
| 653 | |a therapeutic targeting of Wnt signaling | ||
| 653 | |a β-catenin paradox | ||
| 653 | |a molecular targeting | ||
| 653 | |a urothelial cancer | ||
| 653 | |a immune checkpoint inhibitor | ||
| 653 | |a immunotherapy resistance | ||
| 653 | |a IBD | ||
| 653 | |a colitis | ||
| 653 | |a β-catenin mutations | ||
| 653 | |a tumor metabolism | ||
| 653 | |a tumor immunology | ||
| 653 | |a molecular therapeutics | ||
| 653 | |a precision medicine | ||
| 653 | |a astrocytic brain tumors | ||
| 653 | |a DKKs | ||
| 653 | |a GSK3β | ||
| 856 | 4 | 0 | |a www.oapen.org |u https://mdpi.com/books/pdfview/book/5245 |7 0 |z DOAB: download the publication |
| 856 | 4 | 0 | |a www.oapen.org |u https://directory.doabooks.org/handle/20.500.12854/81213 |7 0 |z DOAB: description of the publication |