Targeting Wnt Signaling in Cancer: Opportunities Abound If We Can Avoid the Sword of Damocles

• Tác giả khác: Kahn, Michael (Biên tập viên), Lai, Keane (Biên tập viên)
• Định dạng: Điện tử Chương của sách
• Ngôn ngữ: Tiếng Anh
• Được phát hành: Basel MDPI - Multidisciplinary Digital Publishing Institute 2022
• Những chủ đề: Medicine; Pharmacology; Wnt signaling; synovial sarcoma; TNIK; NCB-0846; MYC; hepatitis B virus; HBV; cancer; liver cancer; β-catenin; TCF/LEF; pancreatic cancer; pancreatic stellate cells; CBP; p300; pancreatitis; fibrosis; just-right signaling; APC; colorectal cancer; RNA-binding proteins; Musashi; drug discovery; Notch signaling; cancer therapy; fungi secondary metabolite derivative; microenvironment; Wnt; AML; drug target; signaling; colorectal; porcupine; R-spondin; serrated; immunotherapy; wnt; vitamin D; colon cancer; L1; Wnt target genes; cell adhesion; NF-κB; invasion and metastasis; cancer stem cells; EMT; Lgr5; Wnt/beta-catenin signaling; angiogenesis; anti-angiogenic therapy; gastrointestinal cancers; therapeutic targeting of Wnt signaling; β-catenin paradox; molecular targeting; urothelial cancer; immune checkpoint inhibitor; immunotherapy resistance; IBD; colitis; β-catenin mutations; tumor metabolism; tumor immunology; molecular therapeutics; precision medicine; astrocytic brain tumors; DKKs; GSK3β
• Truy cập trực tuyến: DOAB: download the publication; DOAB: description of the publication

Dysregulation of Wnt signaling is known to be associated with various cancers. As such, identification of novel Wnt pathway targets in cancer and better characterization of already-known targets present exciting, emerging opportunities for cancer treatment. In this Special Issue, we feature papers w...