Study of intracellular signaling pathways in Chronic Myeloproliferative Neoplasms

A gain-of-function mutation in Janus kinase 2 (JAK2V617F) is at the basis of the majority of chronic myeloproliferative neoplasms (MPN). Enhanced activation of other downstream pathways including the PI3K/mTOR pathway has been documented as well. In this study we evaluated the effects of JAK1/2 inhi...

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Bibliografski detalji
Glavni autor: Martinelli, Serena (auth)
Format: Elektronički Poglavlje knjige
Jezik:engleski
Izdano: Florence Firenze University Press 2017
Serija:Premio Tesi di Dottorato
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