Albumin-Based Drug Delivery Systems

• Other Authors: Katona, Gábor (Editor)
• Format: Electronic Book Chapter
• Language: English
• Published: Basel MDPI - Multidisciplinary Digital Publishing Institute 2022
• Subjects: Medicine; Pharmaceutical industries; plasma half-life extension; albumin conjugation; in vivo glucose-lowering activity; glucagon-like peptide-1; quality by design; rapid equilibrium dialysis; muco-adhesion; brain PAMPA; RPMI 2650 nasal epithelial cell; human serum albumin; dimerization; doxorubicin; enhanced permeability and retention effect; antitumor; Arthrobacter globiformis; gout; half-life extension; inverse electron demand Diels-Alder reaction; site-specific albumin conjugation; thermostability; urate oxidase; albumin; anti-thrombotic; CD39; coating of medical devices; stent coating; therapeutic fusion protein; conjugates; vanadium; cancer; prodrug; hydrogels; EPR/ESR spectroscopy; release behavior; disulfide; glioma; conjugate; albumin binding moieties; peptides; Evans blue; 4-(p-iodophenyl)butyric acid; integrin αvβ6; integrin αvβ6 binding peptide; improved pharmacokinetics; PET imaging
• Online Access: DOAB: download the publication; DOAB: description of the publication

Albumin is playing an increasing role as a versatile, biodegradable drug carrier in clinical theranostics. By applying different techniques, smart drug-delivery systems can be developed from albumin in order to improve drug delivery of different active pharmaceutical ingredients, even small-molecule...