Down Syndrome Neuropsychological Phenotype across the Lifespan

• Other Authors: Pulsifer, Margaret B. (Editor)
• Format: Electronic Book Chapter
• Language: English
• Published: Basel MDPI - Multidisciplinary Digital Publishing Institute 2022
• Subjects: Medicine; Neurosciences; trisomy 21; decoding; vocabulary; letters; phonological awareness; down syndrome; fluency; disfluency; co-occurrence; comorbidity; language; Down syndrome; social cognition; social behavior; measurement; children; attention; audiovisual processing; communicative abilities in infants; Trisomy 21; independence; transition to adulthood; proxy-report; regression; Alzheimer's disease; biomarkers; dementia; cognition; functional independence; neuropsychological assessment; primary care; screening; early regression; idiopathic regression; depression; selective serotonin reuptake inhibitor; mild cognitive impairment; cognitive decline; neuropsychological tests; cognitive function; early-onset Alzheimer disease; late-onset Alzheimer disease; hypothyroidism; thyroid autoantibodies; TSH; Free T4; APOE Ɛ4; autism spectrum disorder; co-occurring; prevalence; n/a
• Online Access: DOAB: download the publication; DOAB: description of the publication

Down syndrome (DS), caused by the triplication of chromosome 21, is the most common genetic cause of intellectual disability (ID). Individuals with DS commonly exhibit unique neuropsychological profiles that emerge during specific developmental stages across the lifespan, often characterized by earl...