Role of MicroRNA in Cancer Development and Treatment

• Other Authors: Pulliero, Alessandra (Editor), Izzotti, Alberto (Editor)
• Format: Electronic Book Chapter
• Language: English
• Published: Basel MDPI - Multidisciplinary Digital Publishing Institute 2022
• Subjects: Medicine; Pharmacology; breast cancer; miRNAs; liquid biopsy; angiogenesis; biomarkers; early diagnosis; air pollution; biomarker; exposure; human; lung cancer; miRNA; carcinogenesis; microRNA; asbestos exposure; oral squamous cell carcinoma; diagnosis; prognosis; saliva; neuroblastoma; MYCN amplification; metastases; chemoresistance; public health genomics; genetic polymorphisms; epigenetic modulations; genetic and microbiome markers; health technology assessment; early disease prevention; nonsmokers lung cancer; environmental risk factors; oncogenes; mutations; glioblastoma; microRNAs; cancer; qPCR; cancer stem cells; plasticizers; in vitro study; PRISMA; no-smokers lung cancer; DNA adducts; mesothelioma; extracellular vesicles; miR-625; fluoro-edenite; asbestos; malignant mesothelioma; cancer prevention; microbiota; epigenetics; environmental pollutants; cutaneous tissues; ozone exposure; n/a
• Online Access: DOAB: download the publication; DOAB: description of the publication

Many researchers around the world have demonstrated that the expression of miRNAs is dysregulated in different tumors. Such dysregulation is caused by multiple mechanisms, and exposure to different carcinogens causes dysregulated epigenetic changes and defects in the miRNA biogenesis machinery. Canc...