Derivatization in Analytical Chemistry

• Other Authors: Tzanavaras, Paraskevas D. (Editor)
• Format: Electronic Book Chapter
• Language: English
• Published: Basel MDPI - Multidisciplinary Digital Publishing Institute 2022
• Subjects: Research & information: general; Chemistry; Analytical chemistry; tyrosine kinase inhibitors; chloranilic acid; charge-transfer reaction; 96-microwell spectrophotometric assay; high-throughput pharmaceutical analysis; biogenic amines; Lycium barbarum L.; HPLC; derivatization; amino acids; esterification; GC-MS; pentafluoropropionic anhydride; stability; toluene; pigment; linseed oil; derivatisation; quantification; P/S ratio; A/P ratio; ∑D; ureide; BSTFA; creatine; creatinine; silylation; TMS; validation; low-molecular-weight thiols; human serum albumin; α-lipoic acid; blood plasma; monobromobimane; reduction; sodium borohydride; high-performance liquid chromatography; fluorescence detection; taurine; glutamine; clams; high-resolution mass spectrometry; nerve agents; methylation; chemical warfare agents; sarin; Novichoks; 2-naphthalenethiol; sulforaphane; HPLC-UV/Vis; pharmacokinetics; acetonitrile-related adducts; acetylenic lipids; double and triple bond localization; in-source derivatization; mass spectrometry; acetazolamide; carbonic anhydrase; enhancement; inhibition; pentafluorobenzyl bromide; chiral metabolomics; rice water; d-amino acids; enantiomer separation; dimethyl labeling; homocysteine thiolactone; homocysteine; zone fluidics; o-phthalaldehyde; fluorosurfactant-modified gold nanoparticles
• Online Access: DOAB: download the publication; DOAB: description of the publication

Derivatization is one of the most widely used sample pretreatment techniques in Analytical Chemistry and Chemical Analysis. Reagent-based or reagent-less schemes offer improved detectability of target compounds, modification of the chromatographic properties and/or the stabilization of sensitive com...