Biomimetic Radical Chemistry and Applications 2021

• Other Authors: Chatgilialoglu, Chryssostomos (Editor)
• Format: Electronic Book Chapter
• Language: English
• Published: Basel MDPI - Multidisciplinary Digital Publishing Institute 2022
• Subjects: Research & information: general; Chemistry; Inorganic chemistry; guanine; guanyl radical; tautomerism; guanine radical cation; oligonucleotides; DNA; G-quadruplex; time-resolved spectroscopies; reactive oxygen species (ROS); oxidation; catalase mimics; peroxide; diiron-peroxo complexes; structure/activity; kinetic studies; biomimetic chemistry; cysteine; ketone reduction; free radicals; pulse radiolysis; kinetics; DNA oxidation; DNA hole transfer; molecular dynamics; quantum dynamics; electron transfer; charge transfer; quantum coherence; chemiluminescence; reaction mechanisms; singlet oxygen; reactive oxygen species; light emission; crosslink; dimerization; protein oxidation; radicals; di-tyrosine; di-tryptophan; disulfides; thiols; aggregation; proteomics; mass spectrometry; collagen; riboflavin; hyaluronic acid; EPR spectroscopy; keratoconus; STEM; DNA biosensor; chemical nucleases; DNA-drug interaction; copper complexes; metallodrugs; MEP pathway; antibiotics; IspH; LytB; [4Fe-4S] cluster; reductive dehydroxylation; bioorganometallic intermediate; inhibitors; methionine; neighboring group effect; hydroxyl radical; triplet state of carboxybenzophenone; one-electron oxidants; laser flash photolysis; peptides; proteins; n/a
• Online Access: DOAB: download the publication; DOAB: description of the publication

The high importance of free radical chemistry for a variety of biological events, including ageing and inflammation, has attracted considerable interest in understanding the related mechanistic steps at the molecular level. Modelling the free radical chemical reactivity of biological systems is an i...