Cell Biology of Galectins

• Other Authors: Timoshenko, Alexander (Editor)
• Format: Electronic Book Chapter
• Language: English
• Published: Basel MDPI - Multidisciplinary Digital Publishing Institute 2022
• Subjects: Research & information: general; Biology, life sciences; galectin-7; p53; MMP-9; cancer; gain-of-function; vasculature; gene expression; tube formation; sprouting; VEGF; integrins; galectin; extracellular matrix; microenvironment; Yersinia enterocolitica; YopP; Galectin-1; nitric oxide; macrophages; epithelial tissues; apoptosis; targeting; inhibitors; β-hairpin; β-sandwich; blood group B; lectin; sugar code; LGALS16; placenta; brain tissues; cell differentiation; transcription factor; miRNA; galectin-3; cardiac fibrosis; heart failure; atrial fibrillation; chronic inflammation; MMPs; microRNAs; lncRNAs; pectin; structure and function; bioactive polysaccharides; galectin-3 inhibition; galacto-oligosaccharides; galectins; intestinal epithelial cells; β-3'galactosyllactose; immunomodulation; mucosal immunity; O-GlcNAc; unconventional secretion; extraembryonic endoderm; n/a
• Online Access: DOAB: download the publication; DOAB: description of the publication

Galectins are a family of soluble beta-galactoside-binding proteins with diverse glycan-dependent and glycan-independent functions outside and inside the cell. There are sixteen recognized mammalian galectin genes, and their expression profiles are very different between cell types, tissues, and spe...