Paradox Role of Oxidative Stress in Cancer State of the Art

• Other Authors: Domenicotti, Cinzia (Editor), Marengo, Barbara (Editor)
• Format: Electronic Book Chapter
• Language: English
• Published: Basel MDPI - Multidisciplinary Digital Publishing Institute 2022
• Subjects: Medicine; Oncology; sonodynamic therapy; carbon doped titanium dioxide; sonosensitizers; ultrasound; cancer treatment; breast cancer treatment; radiotherapy; hematological malignancies; oxidative stress; lymphoma; leukemia; multiple myeloma; apoptosis; mitochondria; ultraviolet-C (UVC); withanolide; combined treatment; oral cancer; DNA damage; cancer therapy; immune system; Hypericum perforatum; hyperforin; reactive oxygen species; pH regulation; tumor prevention; tumor therapy; cancerogenesis; inflammatory signaling; natural compounds; pancreatic cancer; antitumor agents; coordination polymers; bioinorganic chemistry; cold atmospheric plasma; reactive oxygen and nitrogen species; nitrite; cancer stem cells; chemoresistance; glutathione; lipid peroxidation; ZEB-1; GPX4; ferroptosis; HO-1; Nrf2; cancer progression; patients; therapy; prognosis; biomarker; Eprenetapopt; Erastin; glutathione (GSH); SLC7A11; iron; NRF2; n/a
• Online Access: DOAB: download the publication; DOAB: description of the publication

Reactive oxygen species (ROS) are produced by healthy cells and are maintained at physiological levels by antioxidant systems. However, when ROS increase in number, a condition of oxidative stress occurs, leading to many human diseases, including cancer. The relationship between oxidative stress and...