Nanomedicine Formulations Based on PLGA Nanoparticles for Diagnosis, Monitoring and Treatment of Disease: From Bench to Bedside

• Other Authors: Tagit, Oya (Editor)
• Format: Electronic Book Chapter
• Language: English
• Published: Basel MDPI - Multidisciplinary Digital Publishing Institute 2022
• Subjects: Technology: general issues; History of engineering & technology; Materials science; poly(lactic-co-glycolic acid) (PLGA); blood-brain barrier (BBB); current Good Manufacturing Practice (cGMP); Food and Drug Administration (FDA); nanotechnology; PLGA nanoparticles; neurodegenerative diseases; drug delivery; central nervous system; neuroprotective drugs; fluorescent labeling; DiI; coumarin 6; rhodamine 123; Cy5.5; quantum yield; brightness; stability of fluorescent label; confocal microscopy; intracellular internalization; in vivo neuroimaging; double-emulsion method; dry powder inhalation; antigen release; porous PLGA particles; microfluidics; methotrexate; chitosan; PLA/PLGA; sustained release; micro-implant; animal model; minimally invasive; drug delivery system; nanoparticles; poly (lactic-co-glycolic acid) (PLGA); microfluidic; pharmacokinetics (PK) and biodistribution; atorvastatin calcium; poly(lactide-co-glycolide); polymeric nanoparticles; carrageenan induced inflammation; anti-inflammatory; radiolabeled nanoparticles; nuclear medicine; photothermal therapy; phthalocyanine; SKOVip-kat; Katushka; TurboFP635; JO-4; PLGA; orthotopic tumors; 3D culture; spheroids; poly(lactic-co-glycolic acid); nanomedicine; scale-up manufacturing; clinical translation; inline sonication; tangential flow filtration; lyophilization; downstream processing; H. pylori; design of experiments; poly(lactic-co-glycolic) acid; size; cancer; chemoimmunotherapy; immunogenic cell death; immune checkpoint blockade; PNA5 glycopeptide; mas receptor; angiotensin; PLGA diblock copolymer; ester and acid-end capped; double emulsion solvent evaporation; biocompatible; biodegradable; cardiovascular; nanoparticle; solid-state characterization; in vitro; drug release kinetics modeling; PEGylation; amine; emulsion; polyvinyl alcohol (PVA); Pluronic triblock copolymer; trehalose; sucrose; Indomethacin; solvents; stabilizers; morphology; particle-size; encapsulation; drug release; cytotoxicity
• Online Access: DOAB: download the publication; DOAB: description of the publication

Nanomedicine is among the most promising emerging fields that can provide innovative and radical solutions to unmet needs in pharmaceutical formulation development. Encapsulation of active pharmaceutical ingredients within nano-size carriers offers several benefits, namely, protection of the therape...