Clinical and Basic Aspects of Neurofibromatosis Type 1

• अन्य लेखक: Nakayama, Juichiro (संपादक), Yoshida, Yuichi (संपादक)
• स्वरूप: इलेक्ट्रोनिक पुस्तक अध्याय
• भाषा: अंग्रेज़ी
• प्रकाशित: IntechOpen 2022
• विषय: Neurology & clinical neurophysiology
• ऑनलाइन पहुंच: DOAB: download the publication; DOAB: description of the publication

Neurofibromatosis type 1 (NF1), also known as von Recklinghausen disease, is a major monogenic neurocutaneous disorder. The NF1 gene encodes the protein neurofibromin whose dysfunction promotes tumorigenesis in central and peripheral neuronal tissues. In addition to inducing the formation of cutaneo...