Mutagenesis and Mitochondrial-Associated Pathologies

Reactive oxygen species (ROS) and DNA double-strand breaks can result from mitochondrial defects and external sources, such as ionizing radiation. If not repaired properly, pathogenic mutations are generated. Human diseases resulting from inherited mitochondrial defects manifest in organs that physi...

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Bibliographic Details
Other Authors: Fasullo, Michael (Editor), Catala, Angel (Editor)
Format: Electronic Book Chapter
Language:English
Published: IntechOpen 2022
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