Advances in Forensic Genetics

• Other Authors: Morling, Niels (Editor)
• Format: Electronic Book Chapter
• Language: English
• Published: Basel MDPI - Multidisciplinary Digital Publishing Institute 2022
• Subjects: Research & information: general; Biology, life sciences; Genetics (non-medical); TaqMan SNP genotyping; OpenArray™ system; forensic DNA phenotyping; forensic DNA typing; animal forensics; wildlife forensics; cat STRs; dog STRs; cyt b; COI; biogeographic ancestry; pigmentation; skin color; externally visible characteristics; forensic genetics; eye colour; rs12913832; DNA phenotyping; domestic dog (Canis familiaris); canine DNA phenotyping; forensic; proof of concept study; evidence; Y-STR; mtDNA; mitochondria; bio-geographical ancestry; massively parallel sequencing; ancestry informative markers; SNPs; 1000 Genomes; Human Origins SNP array; FDP; HIrisPlex-S; DEPArray; ancestry prediction; phenotype prediction; next-generation sequencing; single-cell genomics; single-cell sequencing; mixture deconvolution; low template DNA; ltDNA; probabilistic genotyping; EuroForMix; DNAStatistX; STRmixTM; DNA forensics; DNA mixture; mixture interpretation; single-cell; clustering algorithm; number of contributors; consensus profile; cross-amplification; microsatellites; Strigiformes; illegal trade; kinship; nocturnal raptors; review; body fluid; organ; tissue; identification; mRNA; DNA methylation; activity level; massively parallel sequencing (MPS); next-generation sequencing (NGS); short tandem repeat (STR); sequence analysis; software; DNA transfer; DNA persistence; DNA prevalence; DNA recovery; activity level evaluation; forensic science; ethics; ethics as lived practice; decision-making; genetic databasing; forensic genealogy; forensic epigenetics; communication; database; SNP; next generation sequencing; hybridization capture; bone; transfer; persistence; activity; Bayesian networks; burglary; CODIS; touch DNA; crime scene; authorized; sampling; short tandem repeat; forensic microbiology; microbiome; physical appearance; human genome variation; DNA-based prediction; investigative leads; forensic DNA intelligence; forensic genomics; degraded DNA; mitochondrial DNA; forensic DNA profiling; ancient DNA; human identification; ancestry; biostatistics; clustering; classification; distance based; likehood; hypothesis tests; DNA molecules; decontamination; cleaning strategies; Romanov family; next generation sequencing (NGS); heteroplasmy; single nucleotide polymorphism (SNP); kinship analyses; biological sexing; DNA; principles of interpretation; investigative; evaluative; reporting; LR; propositions; activity issues
• Online Access: DOAB: download the publication; DOAB: description of the publication

The book has 25 articles about the status and new directions in forensic genetics. Approximately half of the articles are invited reviews, and the remaining articles deal with new forensic genetic methods. The articles cover aspects such as sampling DNA evidence at the scene of a crime; DNA transfer when handling evidence material and how to avoid DNA contamination of items, laboratory, etc.; identification of body fluids and tissues with RNA; forensic microbiome analysis with molecular biology methods as a supplement to the examination of human DNA; forensic DNA phenotyping for predicting visible traits such as eye, hair, and skin colour; new ancestry informative DNA markers for estimating ethnic origin; new genetic genealogy methods for identifying distant relatives that cannot be identified with conventional forensic DNA typing; sensitive DNA methods, including single-cell DNA analysis and other highly specialised and sensitive methods to examine ancient DNA from unidentified victims of war; forensic animal genetics; genetics of visible traits in dogs; statistical tools for interpreting forensic DNA analyses, including the most used IT tools for forensic STR-typing and DNA sequencing; haploid markers (Y-chromosome and mitochondria DNA); inference of ethnic origin; a comprehensive logical framework for the interpretation of forensic genetic DNA data; and an overview of the ethical aspects of modern forensic genetics.