Colorectal Cancers: From Present Problems to Future Solutions

• Other Authors: Allgayer, Heike (Editor)
• Format: Electronic Book Chapter
• Language: English
• Published: Basel MDPI - Multidisciplinary Digital Publishing Institute 2022
• Subjects: Medicine; Oncology; Phage; bacteriophages; diet; infection; colorectal; cancer; nutrition; circulating tumor cells; colorectal cancer; EPISPOT assay; CellSearch® system; predictive value; chromatin density; nanoscale; tumour cell heterogeneity; microRNAs; metastasis; super-resolution microscopy; early onset; cohort; epidemiology; liquid biopsy; biomarker; indirect carcinogenesis; bovine meat and milk factors (BMMF); chronic zoonosis; multiplex; tumor immunology; immune landscape; spontaneous feline intestinal tumors; comparative oncology; tumor budding; CTNNB1; genome-wide methylation array; methylation; miRNA; colon cancer; personalized treatment; drug combinations; Matrix Metalloproteinases (MMPs); polyp; TIMPs; MMP polymorphisms; MMP targeting; S100A4; DKK1; Wnt signaling; patient survival; gender; rectal cancer; radiochemotherapy; radiosensitivity; DNA double-strand breaks; deposited energy; quality of life; blood values; (molecular) carcinogenesis; cancer progression; (single) cancer cell heterogeneity; models; infectious agents; (targeted) therapy; personalized medicine
• Online Access: DOAB: download the publication; DOAB: description of the publication

The scientific community has made significant progress in our molecular understanding of sporadic and hereditary colorectal carcinogenesis and progression. Thie pertains to, e.g., the discovery of (mutated) oncogenes and tumor suppressor genes, microsatellite instabilities, modifications in DNA repa...