New Biomolecules and Drug Delivery Systems as Alternatives to Conventional Antibiotics

• Other Authors: Felgueiras, Helena (Editor)
• Format: Electronic Book Chapter
• Language: English
• Published: Basel MDPI - Multidisciplinary Digital Publishing Institute 2022
• Subjects: Research & information: general; Chemistry; nanoparticles; 4-Nerolidylcatechol; antifungals; Microsporum canis; polycaprolactone; nanoprecipitation; silver nanoparticles; green synthesis method; Catharanthus roseus; Azadirachta indica; multidrug-resistant bacteria; wound healing; nosocomial infection; plant extract; grapefruit seed extract; antibacterial activity; fiber-hydrogel composite; biodegradable polymers; skin regeneration; drug delivery platforms; controlled release; tetramycin; antimicrobial activity; kiwifruit disease; conventional antibiotics; storage quality; gold nanoparticles; flavonoids; Gram-negative bacteria; DNA gyrase; in silico; multidrug-resistant Acinetobacter baumannii (MDR-AB); hypertonic saline; antibiotics; biofilm; aerosol delivery; ultrahigh-throughput screening; live biosensors; antibiotic discovery; gram-negative pathogens; microfluidic droplet cocultivation; efficient promoters; polymyxins; colistin biosynthetic gene cluster; single cell; multi-omics; quercetin; magnesium-doped calcium silicate; osteogenic activity; bone regeneration and nanofiber scaffold; bulk-tank milk; mastitis; methicillin; milk; goat; somatic cell counts; staphylococcus; tetracycline; total bacterial counts; prosthetic joint infection; local prevention; allicin; chitosan; Sphaerotheca sp.; antibiotic; Rosa roxburghii; cyclic diphenylphosphonate; quinoline; DNA gyrase inhibitor; molecular docking; magnesium ion; n/a
• Online Access: DOAB: download the publication; DOAB: description of the publication

New approaches to deal with the growing concern associated with antibiotic-resistant bacteria are in great demand. For many years, antibiotics have widely been employed to treat infections. However, their excessive consumption and misuse have accelerated the rise of antibiotic-resistant microorganisms, which constitute a major challenge to global health. The antibiotic crisis is now a general concern; therefore, alternative biomolecules or drug delivery systems to treat infections are urgently needed. From natural extracts to traditional medicine remedies, to newly engineered nanocapsules and nanoparticles, to bio-based, biodegradable delivery platforms, many systems to fight infections are explored in this book.