Theme Issue Honoring Prof. Dr. Ludger Wessjohann’s 60th Birthday: Natural Products in Modern Drug Discovery

• Andere auteurs: Hussain, Hidayat (Redacteur)
• Formaat: Elektronisch Hoofdstuk
• Taal: Engels
• Gepubliceerd in: Basel MDPI - Multidisciplinary Digital Publishing Institute 2022
• Onderwerpen: Research & information: general; Chemistry; Organic chemistry; multi-component reaction; fusidic acid; TEMPO-conjugate; electron paramagnetic resonance (EPR) spectroscopy; caspase-3; incomptine A; sesquiterpene lactone; Decachaeta incompta; cytotoxic activity; iTRAQ; apoptosis; ROS production; violacein; hepatocellular carcinoma; proliferation; stemness; natural products; tumor microenvironment (TME); lung cancer; phytochemicals; botanical agents; steroidal alkaloids; solanidane alkaloids; demissidine; solanidine; flavonoids; coronavirus; SARS-CoV-2; SARS-CoV; MERS-CoV; anticancer activity; apoptosis resistance; ophiobolin A; polygodial; Wittig reaction; melanoma; tumor heterogeneity; pregnancy; anti-tumor peptides; in vitro model; medicinal herbs; cancer treatment; cancer stem cells; drug resistance; metastasis; RCE-4; PCD; ATG 4B; the Bcl-2-Beclin 1 complex; Sparticola junci; structure elucidation; ECD-TDDFT; COX inhibitory; molecular docking; antiproliferative; cytotoxic; Sepedonium ampullosporum; peptaibols; ampullosporin; glutamic acid methyl ester; solid-phase peptide synthesis; antifungal; anticancer; target identification; kaempferol; docking; DARTS; Src; breast cancer; butein; frondoside-A; STAT3; angiogenesis; invasion; viability; tumor growth; marine fungi; Cosmospora sp.; soudanone; Magnaporthe oryzae; co-culture; phytopathogen; molecular networking; metabolomics; bispecific antibody; Trypsiligase; click chemistry; biorthogonal chemistry; antibody engineering; n/a
• Online toegang: DOAB: download the publication; DOAB: description of the publication

Nature continuously produces biologically useful molecules and provides humankind with life-saving drugs or therapies. Natural products (NPs) offer a vast, unique and fascinating chemical diversity and these molecules have evolved for optimal interactions with biological macromolecules. Moreover, na...