Antimicrobial Peptides Aka Host Defense Peptides - From Basic Research to Therapy

• Other Authors: Petrlova, Jitka (Editor)
• Format: Electronic Book Chapter
• Language: English
• Published: Basel MDPI - Multidisciplinary Digital Publishing Institute 2022
• Subjects: Research & information: general; Chemistry; ECP; AMPs; infection; murine model; Gram-negative bacteria; LPS; host defense peptides; monocytes; neutrophils; neutrophil-monocyte interaction; extracellular traps; host defense peptide; innate immunity; NF-κB; poly I:C; toll-like receptor 3; mucus of Cornu aspersum; peptide fraction MW < 10 kDa; Escherichia coli NBIMCC 8785; SEM; fluorescence and digital assays; antibacterial effect; oral cavity; human cathelicidin; antimicrobial peptides; immunomodulation; oncolytic peptides; cancer; membrane integrity; bulky non-nature amino acid; DAMPs; drug design; antimicrobial peptidomimetic; hydrogel-based system; hyaluronic acid; anti-infective activity; skin infections; antimicrobial peptide; expression; intein; self-cleavage; cecropin-like; apolipoprotein E; host defense; aggregation; body fluid; AMP; interaction network; chemical barrier; cationic antimicrobial peptides; length dependent activity; antimicrobial activity; hemolysis; vesicle leakage; solid-state 31P-, 15N- and 19F-NMR; β-stranded peptides; β-sheets; structure and orientation of peptides in membranes
• Online Access: DOAB: download the publication; DOAB: description of the publication

This Special Issue reprint will address the most current and innovative developments in the field of HDP research across a range of topics, such as structure and function analysis, modes of action, anti-microbial effects, cell and animal model systems, the discovery of novel host-defense peptides, and drug development.