Vitamins C and D Global and Population Health Perspectives

• Other Authors: Carr, Anitra (Editor), Gombart, Adrian (Editor)
• Format: Electronic Book Chapter
• Language: English
• Published: Basel MDPI - Multidisciplinary Digital Publishing Institute 2023
• Subjects: Research & information: general; Biology, life sciences; Food & society; immune system; viral infection; influenza; COVID-19; micronutrients; vitamins; omega-3 fatty acids; minerals; vitamin C; vitamin D; vitamin C status; vitamin C deficiency; global health; dietary intake; obesity; smoking; communicable disease; infection; noncommunicable disease; hypovitaminosis C; low and middle income; LMIC; supplement; non-communicable disease; Vitamin C status; energy; well-being; kiwifruit; mood; SARS-CoV-2; coronavirus; ascorbate; colds; pneumonia; sepsis; immunonutrition; supplementation; dietary surveys; trends; descriptive studies; United States; fruit juice; fruit; vegetables; psychology; mental health; nutrition; healthy adults; ethnicity; Māori; Pasifika; Pacific; Asian; ascorbic acid; post-viral fatigue; lack of concentration; sleep disturbances; depression; frailty; elderly; hospitalisation; serum 25-hydroxyvitamin D; first-generation immigrants; melanin; long COVID; immunisation; immune support; body weight; vitamin C intake; plasma ascorbate concentrations; vitamin C requirements; dietary vitamin C; hyperglycaemia; South Africa; vitamin D receptor; vitamin D-binding protein; n/a
• Online Access: DOAB: download the publication; DOAB: description of the publication

The global coronavirus pandemic has highlighted the paramount importance of immune health and the nutrient status of peoples worldwide. Vitamins C and D have important roles in both the innate and adaptive immune systems and are known to support healthy immune function. Both vitamins C and D have gene regulatory roles with the ability to up- and down-regulate thousands of genes, thus playing pleotropic roles in human health and disease. People from low- and middle-income countries tend to have inadequate micronutrient intakes and status, as do specific subgroups from high-income countries. This can affect their resistance to both communicable and non-communicable diseases and the severity of these diseases. In this Special Issue, we have compiled review articles and research papers (both observational and interventional studies) that explore the role of vitamins C and D in numerous aspects of global and population health.