Biomedical and Pharmacological Applications of Marine Collagen

• Other Authors: Yoon, Sik (Editor)
• Format: Electronic Book Chapter
• Language: English
• Published: Basel MDPI - Multidisciplinary Digital Publishing Institute 2023
• Subjects: Technology: general issues; History of engineering & technology; porifera; demosponges; biomaterial; collagen; spongin; wound healing; lizardfish scale; marine collagen; thermal stability; cell viability; biomechanical properties; collagen membrane; AFM; SEM; tensile test; giant squid; Dosidicus Gigas; jumbo squid; outer tunic; tissue engineering; peptidase; the MEROPS S8 family; bovine bone collagen; oligopeptides; hydrolysate; cisplatin; fish collagen peptides; thymic epithelial cells; reactive oxygen species; apoptosis; MAPK (p38 MAPK, JNK, and ERK) pathway; carbonated hydroxyapatite; fishery by-product; 3D scaffold; bone regeneration; blacktip skin collagens; amino acid profile; protein pattern; microstructure; Col-TPU composite nanofiber membranes; electrospinning; mechanical properties; stromal vascular fraction; vascularization; blue shark skin collagen; 3D constructs
• Online Access: DOAB: download the publication; DOAB: description of the publication

Biomimetic polymers and materials have been widely used in a variety of biomedical and pharmacological applications. Particularly, collagen-based biomaterials have been extensively applied in various biomedical fields, such as scaffolds in tissue engineering. However, there are many challenges associated with the use of mammalian collagen, including the issues of religious constrains, allergic or autoimmune reactions, and the spread of animal diseases. Over the past few decades, marine collagen (MC) has emerged as a promising biomaterial for biomedical and pharmacological applications. Marine organisms are a rich source of structurally novel and biologically active compounds, and to date, many biological components have been isolated from various marine resources. MC offers advantages over mammalian collagen due to its water solubility, low immunogenicity, safety, biocompatibility, antimicrobial activity, functionality, and low production costs. Due to its characteristics and physicobiochemical properties, it has tremendous potential for use as a scaffold biomaterial in tissue engineering and regenerative medicine, in drug delivery systems, and as a therapeutic. In this Special Issue, we encourage submissions related to the recent developments, advancements, trends, challenges, and future perspectives in this new research field. We expect to receive contributions from different areas of multidisciplinary research, including-but not restricted to-extraction, purification, characterization, fabrication, and experimentation of MC, with a particular focus on their biotechnological, biomedical and pharmacological uses.