Light-Controlled Modulation and Analysis of Neuronal Functions

Contemporary research has been enriched by new directions in which light plays a key role as a tool for the modulation of cellular activity and the invasive monitoring of intracellular ions and other components. The progress in molecular biology, imaging techniques and other modern technologies has...

Full description

Saved in:
Bibliographic Details
Other Authors: Bregestovski, Piotr (Editor), Matera, Carlo (Editor)
Format: Electronic Book Chapter
Language:English
Published: Basel MDPI - Multidisciplinary Digital Publishing Institute 2023
Subjects:
Online Access:DOAB: download the publication
DOAB: description of the publication
Tags: Add Tag
No Tags, Be the first to tag this record!

MARC

LEADER 00000naaaa2200000uu 4500
001 doab_20_500_12854_96737
005 20230202
003 oapen
006 m o d
007 cr|mn|---annan
008 20230202s2023 xx |||||o ||| 0|eng d
020 |a books978-3-0365-6562-0 
020 |a 9783036565637 
020 |a 9783036565620 
040 |a oapen  |c oapen 
024 7 |a 10.3390/books978-3-0365-6562-0  |c doi 
041 0 |a eng 
042 |a dc 
072 7 |a GP  |2 bicssc 
072 7 |a PS  |2 bicssc 
100 1 |a Bregestovski, Piotr  |4 edt 
700 1 |a Matera, Carlo  |4 edt 
700 1 |a Bregestovski, Piotr  |4 oth 
700 1 |a Matera, Carlo  |4 oth 
245 1 0 |a Light-Controlled Modulation and Analysis of Neuronal Functions 
260 |a Basel  |b MDPI - Multidisciplinary Digital Publishing Institute  |c 2023 
300 |a 1 electronic resource (200 p.) 
336 |a text  |b txt  |2 rdacontent 
337 |a computer  |b c  |2 rdamedia 
338 |a online resource  |b cr  |2 rdacarrier 
506 0 |a Open Access  |2 star  |f Unrestricted online access 
520 |a Contemporary research has been enriched by new directions in which light plays a key role as a tool for the modulation of cellular activity and the invasive monitoring of intracellular ions and other components. The progress in molecular biology, imaging techniques and other modern technologies has led to the emergence of three main areas in which light is the main tool: optogenetics, photopharmacology, and optosensorics. The main advantages of these approaches are the possibilities to investigate the functions of cells; modulate the activity of ion channels, synaptic transmission and neuronal circuits; measure concentrations of ions and other cellular components; and even control the behaviour of organisms.Due to the development of these powerful molecular and genetic tools, our understanding of the mechanisms underlying the functioning of the nervous system has greatly advanced. This reprint is intended to highlight the latest advances in these areas with a primary focus on light-based analysis and control of neuronal functions. 
540 |a Creative Commons  |f https://creativecommons.org/licenses/by/4.0/  |2 cc  |4 https://creativecommons.org/licenses/by/4.0/ 
546 |a English 
650 7 |a Research & information: general  |2 bicssc 
650 7 |a Biology, life sciences  |2 bicssc 
653 |a parietal association cortex 
653 |a fear memory 
653 |a c-fos 
653 |a calcium activity 
653 |a transgenic mice 
653 |a two-photon imaging 
653 |a neuromuscular junction 
653 |a neurotransmitter release 
653 |a acetylcholine 
653 |a nicotinic receptor 
653 |a calcium channel 
653 |a calcium transient 
653 |a Parkinson's disease 
653 |a α-synuclein 
653 |a neurogenesis 
653 |a neural stem cell 
653 |a neural progenitor cell 
653 |a astrocyte 
653 |a optogenetics 
653 |a astrocytes 
653 |a hippocampal neurons 
653 |a patch-clamp 
653 |a channelrhodopsin-2 
653 |a opto-α1-adrenoreceptor 
653 |a photopharmacology 
653 |a photoswitchable ligands 
653 |a ion channels 
653 |a voltage-gated ion channels 
653 |a ligand-gated ion channels 
653 |a homology modeling 
653 |a molecular docking 
653 |a molecular dynamics 
653 |a enhanced sampling 
653 |a genetically encoded biosensors 
653 |a optopharmacology 
653 |a intracellular pH 
653 |a intracellular chloride 
653 |a brain slices 
653 |a pH and Cl− transporters 
653 |a Ca2+ indicators 
653 |a calcium in vivo imaging 
653 |a place cells 
653 |a place fields 
653 |a cognitive maps 
653 |a ENaC 
653 |a phosphoinositides 
653 |a PIP2 
653 |a optogenetic 
653 |a CRY2 
653 |a sodium channel 
653 |a CoroNa Green 
653 |a azobenzene 
653 |a behavior 
653 |a brainwave 
653 |a dopamine 
653 |a GPCR 
653 |a in vivo electrophysiology 
653 |a photochromism 
653 |a photoswitch 
653 |a zebrafish 
653 |a neural plasticity 
653 |a tropomyosin kinase receptor B 
653 |a parvalbumin-positive interneurons 
653 |a calcium/calmodulin positive pyramidal neurons 
653 |a V1/visual cortex 
653 |a multiple regression with interaction and simple slopes analysis 
653 |a n/a 
856 4 0 |a www.oapen.org  |u https://mdpi.com/books/pdfview/book/6683  |7 0  |z DOAB: download the publication 
856 4 0 |a www.oapen.org  |u https://directory.doabooks.org/handle/20.500.12854/96737  |7 0  |z DOAB: description of the publication