Light-Controlled Modulation and Analysis of Neuronal Functions

• Rannpháirtithe: Bregestovski, Piotr (Eagarthóir), Matera, Carlo (Eagarthóir)
• Formáid: Leictreonach Caibidil leabhair
• Teanga: Béarla
• Foilsithe / Cruthaithe: Basel MDPI - Multidisciplinary Digital Publishing Institute 2023
• Ábhair: Research & information: general; Biology, life sciences; parietal association cortex; fear memory; c-fos; calcium activity; transgenic mice; two-photon imaging; neuromuscular junction; neurotransmitter release; acetylcholine; nicotinic receptor; calcium channel; calcium transient; Parkinson's disease; α-synuclein; neurogenesis; neural stem cell; neural progenitor cell; astrocyte; optogenetics; astrocytes; hippocampal neurons; patch-clamp; channelrhodopsin-2; opto-α1-adrenoreceptor; photopharmacology; photoswitchable ligands; ion channels; voltage-gated ion channels; ligand-gated ion channels; homology modeling; molecular docking; molecular dynamics; enhanced sampling; genetically encoded biosensors; optopharmacology; intracellular pH; intracellular chloride; brain slices; pH and Cl− transporters; Ca2+ indicators; calcium in vivo imaging; place cells; place fields; cognitive maps; ENaC; phosphoinositides; PIP2; optogenetic; CRY2; sodium channel; CoroNa Green; azobenzene; behavior; brainwave; dopamine; GPCR; in vivo electrophysiology; photochromism; photoswitch; zebrafish; neural plasticity; tropomyosin kinase receptor B; parvalbumin-positive interneurons; calcium/calmodulin positive pyramidal neurons; V1/visual cortex; multiple regression with interaction and simple slopes analysis; n/a
• Rochtain ar líne: DOAB: download the publication; DOAB: description of the publication

Contemporary research has been enriched by new directions in which light plays a key role as a tool for the modulation of cellular activity and the invasive monitoring of intracellular ions and other components. The progress in molecular biology, imaging techniques and other modern technologies has...