Virus-Host Cell Interactions

• Other Authors: Hoenen, Thomas (Editor), Groseth, Allison (Editor)
• Format: Electronic Book Chapter
• Language: English
• Published: Basel MDPI - Multidisciplinary Digital Publishing Institute 2023
• Subjects: Research & information: general; Biology, life sciences; Microbiology (non-medical); influenza; Staphylococcus aureus; alveolar-capillary barrier; coinfection; kinome; virulence factor; virus; RNA; modification; epitranscriptomic; N6-methyladenosine; mapping; 5-methylcytosine; pseudouridine; HIV-1; Nipah virus; endothelial cells; smooth muscle cells; henipavirus; paramyxovirus; bat virus; fusion; syncytia; neutrophils; arboviruses; mosquito; inflammation; pathology; negative strand RNA viruses (NSV); viral inclusion bodies; biomolecular condensates; liquid-liquid phase separation (LLPS); viral replication; nucleoprotein; phosphoprotein; capsid uncoating; HDAC6; ubiquitin; EPS8; TNPO1; pandemic; M1; virus-host interaction; Chikungunya virus; CHIKV; alphavirus; enveloped virus; phosphatidylserine; T-cell immunoglobulin and mucin domain 1; TIM-1; Axl receptor tyrosine kinase; Axl; entry; Ebola virus; Marburg virus; HERC5; antiviral; interferon; positive-strand RNA viruses; replication organelle; viral replication complex; membrane alterations; electron microscopy; n/a
• Online Access: DOAB: download the publication; DOAB: description of the publication

Viruses are obligate intracellular parasites, and their biology is closely interlinked with that of their host cells. However, this relationship is two-sided. Virus-host cell interactions are clearly essential to allow viruses to facilitate their life cycles, but they also give the host cell a chance to recognize and combat virus infections. This Special Issue of Cells compiles review papers on emerging themes related to virus-host cell interactions of RNA viruses, including mechanistic details of virus uncoating, new insights into the nature and function of viral replication compartments, and the role of RNA methylation in the virus life cycle. This is complemented by primary research papers addressing virus-host cell interactions from diverse perspectives.