Amyloid-β Structure, Function, and Pathophysiological Significance in Neurodegenerative Diseases

• अन्य लेखक: Tanaka, Masashi (संपादक), Ono, Kenjiro (संपादक), Saito, Satoshi (संपादक)
• स्वरूप: इलेक्ट्रोनिक पुस्तक अध्याय
• भाषा: अंग्रेज़ी
• प्रकाशित: Basel MDPI - Multidisciplinary Digital Publishing Institute 2023
• विषय: Public health & preventive medicine; activation phenotypes; microglia; neuroinflammation; immunohistochemistry; temporal cortex; Alzheimer's disease; amyloid; amyloid β-protein (Aβ); mAb158; oligomers; protofibrils; amyloid aggregation; supported lipid bilayers; time-lapse AFM; molecular dynamics simulation; alzheimer's disease; amyloid β; bryostatin-1; ECE1; iPS; nELAV; neurotoxicity; oligomer; protein kinase C; α-secretase; APP mutation; recessive inheritance; familial Alzheimer's disease; Aβ oligomers; amyloid imaging; microbiota; bacterial amyloid; FUBA; curli; CsgA; amyloid beta; oxidative stress; supplement; phosphodiesterase III inhibitor; cerebral micro-hemorrhage(s); cerebral amyloid angiopathy; amyloid-β protein; transgenic mice; NMR; CD; Aβ; β-amyloid peptide; α/β-discordant; Dutch-type mutation; E22Q; FAD; Amyloid β; Polyphenol; Pro-oxidant; Alzheimer's Disease; molecular imaging; amyloid β-peptides; islet amyloid polypeptide; high-speed atomic force microscopy; amyloid PET; tau PET; amyloid precursor protein; mutation; cerebellum; PBB3; PiB; axon; traditional medicines; Polygalae Radix; diosgenin; naringenin; kihito; amyloid-β; antimicrobial; antiviral; antimicrobial peptide; neurodegenerative disease; misfolding; fluorescence microscopy; FRET; n/a
• ऑनलाइन पहुंच: DOAB: download the publication; DOAB: description of the publication

सारांश

This reprint includes 16 original articles published in a Special Issue that focuses on the pathological significance of amyloid-β in neurodegenerative diseases, such as Alzheimer's disease, the main cause of dementia. Collections in this reprint provide novel insights into the underlying mechanisms and therapeutic potentials of repositioning drugs and new agents for Alzheimer's disease and related dementias. These findings are expected to contribute to the development of innovative strategies for the prevention and treatment of such diseases.

भौतिक वर्णन

1 electronic resource (276 p.)

आईएसबीएन

books978-3-0365-6713-6
9783036567129
9783036567136

अभिगमन

Open Access