Amyloid-β Structure, Function, and Pathophysiological Significance in Neurodegenerative Diseases

• Other Authors: Tanaka, Masashi (Editor), Ono, Kenjiro (Editor), Saito, Satoshi (Editor)
• Format: Electronic Book Chapter
• Language: English
• Published: Basel MDPI - Multidisciplinary Digital Publishing Institute 2023
• Subjects: Public health & preventive medicine; activation phenotypes; microglia; neuroinflammation; immunohistochemistry; temporal cortex; Alzheimer's disease; amyloid; amyloid β-protein (Aβ); mAb158; oligomers; protofibrils; amyloid aggregation; supported lipid bilayers; time-lapse AFM; molecular dynamics simulation; alzheimer's disease; amyloid β; bryostatin-1; ECE1; iPS; nELAV; neurotoxicity; oligomer; protein kinase C; α-secretase; APP mutation; recessive inheritance; familial Alzheimer's disease; Aβ oligomers; amyloid imaging; microbiota; bacterial amyloid; FUBA; curli; CsgA; amyloid beta; oxidative stress; supplement; phosphodiesterase III inhibitor; cerebral micro-hemorrhage(s); cerebral amyloid angiopathy; amyloid-β protein; transgenic mice; NMR; CD; Aβ; β-amyloid peptide; α/β-discordant; Dutch-type mutation; E22Q; FAD; Amyloid β; Polyphenol; Pro-oxidant; Alzheimer's Disease; molecular imaging; amyloid β-peptides; islet amyloid polypeptide; high-speed atomic force microscopy; amyloid PET; tau PET; amyloid precursor protein; mutation; cerebellum; PBB3; PiB; axon; traditional medicines; Polygalae Radix; diosgenin; naringenin; kihito; amyloid-β; antimicrobial; antiviral; antimicrobial peptide; neurodegenerative disease; misfolding; fluorescence microscopy; FRET; n/a
• Online Access: DOAB: download the publication; DOAB: description of the publication

This reprint includes 16 original articles published in a Special Issue that focuses on the pathological significance of amyloid-β in neurodegenerative diseases, such as Alzheimer's disease, the main cause of dementia. Collections in this reprint provide novel insights into the underlying mecha...