New Insights in the Research of Bioactive Compounds from Plant Origin with Nutraceutical and Pharmaceutical Potential

• Other Authors: Dincheva, Ivayla (Editor), Badjakov, Ilian (Editor), Galunska, Bistra (Editor)
• Format: Electronic Book Chapter
• Language: English
• Published: Basel MDPI - Multidisciplinary Digital Publishing Institute 2023
• Subjects: Research & information: general; Biology, life sciences; Thymus vulgaris; biofilm; DPPH; P. fluorescens; S. enteritidis; Syzygium aromaticum; in vitro; in situ; antimicrobial activity; antibiofilm activity; secondary metabolites; GC-MS; mass-spectra; bioactive compounds; nano-carrier system; magnetic nanoparticles; Sambucus ebulus L.; phytochemical composition; anti-inflammatory; ER stress; lipopolysaccharides; macrophages; Prunus persica L.; gas chromatography-mass spectrometry (GC-MS); volatile compounds; principal component analysis (PCA); hierarchical cluster analysis (HCA); headspace-solid phase micro extraction (HS-SPME); jacaranones; Crepis pulchra; Cichorioideae; Asteraceae; antiproliferative activity; Moldavian dragonhead; phytochemicals; large-scale distillation; in vitro biological activity; time-kill kinetics modeling; Bulgaria; Bosnia; Corsica; France; essential oil; Helichrysum; protected species; α-pinene; sabinene; neryl acetate; Artemisia tridentata; A. longifolia; A. ludoviciana; A. cana; camphor; antioxidant; eucalyptol; cis-thujone; α-necrodol-acetate; Burkillanthus malaccensis; antibiotic potentiator; werneria chromene; dihydroxyacidissiminol; SARS-CoV-2; cathepsin L; nsp13 helicase; spike protein; androgenetic alopecia; anti-hair loss; hair growth promotion; shallot; Allium ascalonicum; 5α-reductase; SRD5A2; Wnt/β-catenin; pinosylvin; pharmacological property; signaling pathway; antimicrobial; cancer; ethnopharmacologic effect; herbal medicine; Ranunculus species; antidiabetic activity; diabetes; DIA-DB web server; flavonoids; in silico study; mechanism of action; phenolic acids; terpenes; Aronia melanocarpa; fruit juice; polyphenols; functional foods; Plantago lanceolata; derivative products; antitumor activity; prebiotic activity; functional annotation; Galphimia spp.; transcriptome; n/a
• Online Access: DOAB: download the publication; DOAB: description of the publication

Plant bioactive compounds are essential for human health due to their multiple biological effects, such as antioxidant, anticarcinogenic, antiallergenic, anti-inflammatory, antimutagenic, and antimicrobial activities leading to beneficial effects on various non-communicable diseases, such as autoimmune, inflammatory, cardiovascular, cancer, metabolic, and neurodegenerative diseases. Identifying these components, as well as establishing their beneficial health effects, will contribute to the discovery of therapeutics for the prevention and treatment of various disorders. Additionally, the screening of natural sources for novel biologically active metabolites is an essential part of several drug discovery programs.This Special Issue aims to present recent developments in high-throughput and efficient analytical approaches enabling the identification of plant-based compounds, the establishment of new protocols for the evaluation of bioactivities, and methods for the extraction, isolation, and structural characterization of new bioactive components with nutraceutical and therapeutic potential.