Plant and Marine-Derived Natural Product Research in Drug Discovery: Strengths and Perspective

• Other Authors: Duarte, Noelia (Editor)
• Format: Electronic Book Chapter
• Language: English
• Published: Basel MDPI - Multidisciplinary Digital Publishing Institute 2023
• Subjects: Research & information: general; Chemistry; propyl-propane-thiosulfinate; propyl-propane-thiosulfonate; antibacterial activity; antifungal activity; vapor; mycosporines; mycosporine-like amino acids (MAAs); mass spectrometry; database; photoprotective compounds; UV-absorbing compounds; melatonin; endoplasmic reticulum stress; diabesity; kidney; cellulite; essential oil; monoterpenes; Thai herbal compress; adipogenesis; lipolysis; vasorelaxation; Asphodelus ramosus; root-tubers; inulin; fructans; fructooligosaccharide; alkaline extraction; high-performance thin layer chromatography; NMR spectroscopy; 2D NMR analyses; infrared spectroscopy; isofuranodiene; Smyrnium olusatrum L.; ischemic stroke; NF-ĸB; IL-1β; TNF-α; Plectranthus; royleanone; 7α-acetoxy-6β-hydroxyroyleanone; ent-abietane; antitumoral activity; antimicrobial activity; antioxidant; Euphorbia; flavonoids; pharmacological activities; structure-activity relationship; Sambucus nigra L.; ethosomes; collagenase inhibition; skin compatibility; anthocyanins; antioxidants; dietary source; bioavailability; biological activity; biosynthesis; Posidonia oceanica; autophagy; lipid accumulation; NAFLD; herbal medicine; amphotericin B; candidiasis; gel; Bursera graveolens; topical treatment; linarin; chemotaxonomy; phytochemistry; bioactivities; (−)-usnic acid; evernic acid; salazinic acid; secondary metabolites; lichen extracts; Garcinia indica; kokum; wild mangosteen; pharmacological activity; terpenoids; Trypanosoma; human African trypanosomiasis; sleeping disease; human American trypanosomiasis; Chagas disease; anticancer activity; cytotoxicity; Hymenocardia acida; nanoencapsulation; nanoparticle; plant extract; PLGA; n/a
• Online Access: DOAB: download the publication; DOAB: description of the publication

Summary

For centuries, nature has been an inspirational source for the discovery of drugs used in modern medicine. Nowadays, natural-based treatments continue to be employed for primary health care, particularly playing a significant role in folk medicine. In addition, we are currently observing an increasing use of natural-products-based supplements from botanical and marine sources, making their standardization and scientific validation a priority to guarantee the safety of these products. Natural products and/or synthetic derivatives using their novel structures have also been of utmost importance in drug discovery and development in several clinical areas. After a period of discreditation and reduced investment, we are now witnessing a renewed interest from the pharmaceutical industry and scientific community due to the urgent need to develop new drugs. This reprint comprises 11 original and 6 review articles dedicated to plant and marine natural products research, contributing to the scientific validation of their use and opening new perspectives in drug discovery

Physical Description

1 electronic resource (346 p.)

ISBN

books978-3-0365-6810-2
9783036568119
9783036568102

Access

Open Access